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901 results

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Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.
Barayeu U, Schilling D, Eid M, Xavier da Silva TN, Schlicker L, Mitreska N, Zapp C, Gräter F, Miller AK, Kappl R, Schulze A, Friedmann Angeli JP, Dick TP. Barayeu U, et al. Among authors: schulze a. Nat Chem Biol. 2023 Jan;19(1):28-37. doi: 10.1038/s41589-022-01145-w. Epub 2022 Sep 15. Nat Chem Biol. 2023. PMID: 36109647 Free PMC article.
Ferroptosis: The Greasy Side of Cell Death.
Friedmann Angeli JP, Miyamoto S, Schulze A. Friedmann Angeli JP, et al. Among authors: schulze a. Chem Res Toxicol. 2019 Mar 18;32(3):362-369. doi: 10.1021/acs.chemrestox.8b00349. Epub 2019 Jan 31. Chem Res Toxicol. 2019. PMID: 30653290 Review.
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M. Doll S, et al. Among authors: schulze a. Nature. 2019 Nov;575(7784):693-698. doi: 10.1038/s41586-019-1707-0. Epub 2019 Oct 21. Nature. 2019. PMID: 31634899
c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis.
Vollmuth N, Schlicker L, Guo Y, Hovhannisyan P, Janaki-Raman S, Kurmasheva N, Schmitz W, Schulze A, Stelzner K, Rajeeve K, Rudel T. Vollmuth N, et al. Among authors: schulze a. Elife. 2022 Sep 26;11:e76721. doi: 10.7554/eLife.76721. Elife. 2022. PMID: 36155135 Free PMC article.
Fatty acid synthesis enables brain metastasis.
Vogel FCE, Schulze A. Vogel FCE, et al. Among authors: schulze a. Nat Cancer. 2021 Apr;2(4):374-376. doi: 10.1038/s43018-021-00202-y. Nat Cancer. 2021. PMID: 35122002 No abstract available.
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer.
Maier CR, Hartmann O, Prieto-Garcia C, Al-Shami KM, Schlicker L, Vogel FCE, Haid S, Klann K, Buck V, Münch C, Schmitz W, Einig E, Krenz B, Calzado MA, Eilers M, Popov N, Rosenfeldt MT, Diefenbacher ME, Schulze A. Maier CR, et al. Among authors: schulze a. Cell Death Differ. 2023 Jul;30(7):1710-1725. doi: 10.1038/s41418-023-01173-6. Epub 2023 May 18. Cell Death Differ. 2023. PMID: 37202505 Free PMC article.
13C-SpaceM: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer.
Buglakova E, Ekelöf M, Schwaiger-Haber M, Schlicker L, Molenaar MR, Mohammed S, Stuart L, Eisenbarth A, Hilsenstein V, Patti GJ, Schulze A, Snaebjornsson MT, Alexandrov T. Buglakova E, et al. Among authors: schulze a. bioRxiv [Preprint]. 2024 Feb 28:2023.08.18.553810. doi: 10.1101/2023.08.18.553810. bioRxiv. 2024. PMID: 38464218 Free PMC article. Preprint.
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A. Kalogirou C, et al. Among authors: schulze a. Nat Commun. 2021 Aug 20;12(1):5066. doi: 10.1038/s41467-021-25325-9. Nat Commun. 2021. PMID: 34417456 Free PMC article.
Lipids as mediators of cancer progression and metastasis.
Vogel FCE, Chaves-Filho AB, Schulze A. Vogel FCE, et al. Among authors: schulze a. Nat Cancer. 2024 Jan;5(1):16-29. doi: 10.1038/s43018-023-00702-z. Epub 2024 Jan 25. Nat Cancer. 2024. PMID: 38273023 Review.
901 results