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p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Gebel J, Tuppi M, Chaikuad A, Hötte K, Schröder M, Schulz L, Löhr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dötsch V. Gebel J, et al. Among authors: schulz l. Nat Chem Biol. 2020 Oct;16(10):1078-1086. doi: 10.1038/s41589-020-0600-3. Epub 2020 Jul 27. Nat Chem Biol. 2020. PMID: 32719556
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I. Shin D, et al. Among authors: schulz l. Nature. 2020 Nov;587(7835):657-662. doi: 10.1038/s41586-020-2601-5. Epub 2020 Jul 29. Nature. 2020. PMID: 32726803 Free PMC article.
High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance.
Cortés-López M, Schulz L, Enculescu M, Paret C, Spiekermann B, Quesnel-Vallières M, Torres-Diz M, Unic S, Busch A, Orekhova A, Kuban M, Mesitov M, Mulorz MM, Shraim R, Kielisch F, Faber J, Barash Y, Thomas-Tikhonenko A, Zarnack K, Legewie S, König J. Cortés-López M, et al. Among authors: schulz l. Nat Commun. 2022 Sep 22;13(1):5570. doi: 10.1038/s41467-022-31818-y. Nat Commun. 2022. PMID: 36138008 Free PMC article.
An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Kang HS, Sánchez-Rico C, Ebersberger S, Sutandy FXR, Busch A, Welte T, Stehle R, Hipp C, Schulz L, Buchbender A, Zarnack K, König J, Sattler M. Kang HS, et al. Among authors: schulz l. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7140-7149. doi: 10.1073/pnas.1913483117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188783 Free PMC article.
Heterochromatin focuses on senescence.
Schulz L, Tyler J. Schulz L, et al. Mol Cell. 2005 Jan 21;17(2):168-70. doi: 10.1016/j.molcel.2005.01.003. Mol Cell. 2005. PMID: 15664186 Free article.
SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells.
Ambrożek-Latecka M, Kozlowski P, Hoser G, Bandyszewska M, Hanusek K, Nowis D, Gołąb J, Grzanka M, Piekiełko-Witkowska A, Schulz L, Hornung F, Deinhardt-Emmer S, Kozlowska E, Skirecki T. Ambrożek-Latecka M, et al. Among authors: schulz l. Cell Death Discov. 2024 Apr 25;10(1):191. doi: 10.1038/s41420-024-01966-9. Cell Death Discov. 2024. PMID: 38664396 Free PMC article.
In praise of folly: flexible goals and human cognition.
Chu J, Tenenbaum JB, Schulz LE. Chu J, et al. Among authors: schulz le. Trends Cogn Sci. 2024 Apr 13:S1364-6613(24)00059-7. doi: 10.1016/j.tics.2024.03.006. Online ahead of print. Trends Cogn Sci. 2024. PMID: 38616478 Review.
518 results