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Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.
Neumann J, Riek-Burchardt M, Herz J, Doeppner TR, König R, Hütten H, Etemire E, Männ L, Klingberg A, Fischer T, Görtler MW, Heinze HJ, Reichardt P, Schraven B, Hermann DM, Reymann KG, Gunzer M. Neumann J, et al. Among authors: schraven b. Acta Neuropathol. 2015 Feb;129(2):259-77. doi: 10.1007/s00401-014-1355-2. Epub 2014 Nov 13. Acta Neuropathol. 2015. PMID: 25391494
Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells.
Horn J, Wang X, Reichardt P, Stradal TE, Warnecke N, Simeoni L, Gunzer M, Yablonski D, Schraven B, Kliche S. Horn J, et al. Among authors: schraven b. J Immunol. 2009 Nov 1;183(9):5756-67. doi: 10.4049/jimmunol.0900649. Epub 2009 Oct 7. J Immunol. 2009. PMID: 19812192
G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.
Köhler A, De Filippo K, Hasenberg M, van den Brandt C, Nye E, Hosking MP, Lane TE, Männ L, Ransohoff RM, Hauser AE, Winter O, Schraven B, Geiger H, Hogg N, Gunzer M. Köhler A, et al. Among authors: schraven b. Blood. 2011 Apr 21;117(16):4349-57. doi: 10.1182/blood-2010-09-308387. Epub 2011 Jan 11. Blood. 2011. PMID: 21224471 Free PMC article.
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.
Hasenberg A, Hasenberg M, Männ L, Neumann F, Borkenstein L, Stecher M, Kraus A, Engel DR, Klingberg A, Seddigh P, Abdullah Z, Klebow S, Engelmann S, Reinhold A, Brandau S, Seeling M, Waisman A, Schraven B, Göthert JR, Nimmerjahn F, Gunzer M. Hasenberg A, et al. Among authors: schraven b. Nat Methods. 2015 May;12(5):445-52. doi: 10.1038/nmeth.3322. Epub 2015 Mar 16. Nat Methods. 2015. PMID: 25775045
216 results