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Recent metabolomic developments for antimalarial drug discovery.
Mamede L, Fall F, Schoumacher M, Ledoux A, De Tullio P, Quetin-Leclercq J, Frédérich M. Mamede L, et al. Among authors: schoumacher m. Parasitol Res. 2022 Dec;121(12):3351-3380. doi: 10.1007/s00436-022-07673-7. Epub 2022 Oct 4. Parasitol Res. 2022. PMID: 36194273 Free article. Review.
Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identified by metabolomics.
Lambert V, Hansen S, Schoumacher M, Lecomte J, Leenders J, Hubert P, Herfs M, Blacher S, Carnet O, Yip C, Blaise P, Duchateau E, Locht B, Thys M, Cavalier E, Gothot A, Govaerts B, Rakic JM, Noel A, de Tullio P. Lambert V, et al. Among authors: schoumacher m. J Mol Med (Berl). 2020 Dec;98(12):1737-1751. doi: 10.1007/s00109-020-01994-9. Epub 2020 Oct 20. J Mol Med (Berl). 2020. PMID: 33079232
Innovative workflow for the identification of cathepsin K cleavage sites in type I collagen.
Demeuse J, Massonnet P, Schoumacher M, Grifnée E, Huyghebaert L, Dubrowski T, Peeters S, Le Goff C, Cavalier E. Demeuse J, et al. Among authors: schoumacher m. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Aug 1;1228:123864. doi: 10.1016/j.jchromb.2023.123864. Epub 2023 Aug 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37634391
Development and validation of an LC-MS/MS method for the simultaneous quantitation of angiotensin (1-7), (1-8), (1-9) and (1-10) in human plasma.
Demeuse J, Huyghebaert L, Determe W, Schoumacher M, Grifnée E, Massonnet P, Dubrowski T, Rechchad M, Segura JF, Peeters S, Cavalier E, Le Goff C. Demeuse J, et al. Among authors: schoumacher m. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Jan 1;1232:123943. doi: 10.1016/j.jchromb.2023.123943. Epub 2023 Nov 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2024. PMID: 38039597
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Thijssen R, Diepstraten ST, Moujalled D, Chew E, Flensburg C, Shi MX, Dengler MA, Litalien V, MacRaild S, Chen M, Anstee NS, Reljić B, Gabriel SS, Djajawi TM, Riffkin CD, Aubrey BJ, Chang C, Tai L, Xu Z, Morley T, Pomilio G, Bruedigam C, Kallies A, Stroud DA, Bajel A, Kluck RM, Lane SW, Schoumacher M, Banquet S, Majewski IJ, Strasser A, Roberts AW, Huang DCS, Brown FC, Kelly GL, Wei AH. Thijssen R, et al. Among authors: schoumacher m. Blood. 2021 May 20;137(20):2721-2735. doi: 10.1182/blood.2020010167. Blood. 2021. PMID: 33824975 Free PMC article.
Cotargeting BCL-2 and MCL-1 in high-risk B-ALL.
Moujalled DM, Hanna DT, Hediyeh-Zadeh S, Pomilio G, Brown L, Litalien V, Bartolo R, Fleming S, Chanrion M, Banquet S, Maragno AL, Kraus-Berthier L, Schoumacher M, Mullighan CG, Georgiou A, White CA, Lessene G, Huang DCS, Roberts AW, Geneste O, Rasmussen L, Davis MJ, Ekert PG, Wei A, Ng AP, Khaw SL. Moujalled DM, et al. Among authors: schoumacher m. Blood Adv. 2020 Jun 23;4(12):2762-2767. doi: 10.1182/bloodadvances.2019001416. Blood Adv. 2020. PMID: 32569380 Free PMC article.
33 results