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Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma.
Kim Y, Jung KY, Kim YH, Xu P, Kang BE, Jo Y, Pandit N, Kwon J, Gariani K, Gariani J, Lee J, Verbeek J, Nam S, Bae SJ, Ha KT, Yi HS, Shong M, Kim KH, Kim D, Jung HJ, Lee CW, Kim KR, Schoonjans K, Auwerx J, Ryu D. Kim Y, et al. Among authors: schoonjans k. Drug Resist Updat. 2024 Mar;73:101054. doi: 10.1016/j.drup.2024.101054. Epub 2024 Jan 17. Drug Resist Updat. 2024. PMID: 38277756 Free PMC article.
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1.
Rodríguez-Agudo R, González-Recio I, Serrano-Maciá M, Bravo M, Petrov P, Blaya D, Herranz JM, Mercado-Gómez M, Rejano-Gordillo CM, Lachiondo-Ortega S, Gil-Pitarch C, Azkargorta M, Van Liempd SM, Martinez-Cruz LA, Simão AL, Elortza F, Martín C, Nevzorova YA, Cubero FJ, Delgado TC, Argemi J, Bataller R, Schoonjans K, Banales JM, Castro RE, Sancho-Bru P, Avila MA, Julve J, Jover R, Mabe J, Simon J, Goikoetxea-Usandizaga N, Martínez-Chantar ML. Rodríguez-Agudo R, et al. Among authors: schoonjans k. JHEP Rep. 2023 Sep 30;6(1):100918. doi: 10.1016/j.jhepr.2023.100918. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38192540 Free PMC article.
Asparagine protects pericentral hepatocytes during acute liver injury.
Sun Y, Demagny H, Faure A, Pontanari F, Jalil A, Bresciani N, Yildiz E, Korbelius M, Perino A, Schoonjans K. Sun Y, et al. Among authors: schoonjans k. J Clin Invest. 2023 Apr 3;133(7):e163508. doi: 10.1172/JCI163508. J Clin Invest. 2023. PMID: 36719750 Free PMC article.
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis.
Li H, Perino A, Huang Q, Von Alvensleben GVG, Banaei-Esfahani A, Velazquez-Villegas LA, Gariani K, Korbelius M, Bou Sleiman M, Imbach J, Sun Y, Li X, Bachmann A, Goeminne LJE, Gallart-Ayala H, Williams EG, Ivanisevic J, Auwerx J, Schoonjans K. Li H, et al. Among authors: schoonjans k. Cell Metab. 2022 Oct 4;34(10):1594-1610.e4. doi: 10.1016/j.cmet.2022.08.015. Epub 2022 Sep 12. Cell Metab. 2022. PMID: 36099916 Free PMC article.
194 results