Schooley RT - Search Results

1

Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs.

Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. bioRxiv [Preprint]. 2021 Jun 7:2020.08.26.269159. doi: 10.1101/2020.08.26.269159. bioRxiv. 2021. PMID: 32869033 Free PMC article. Updated. Preprint.

2

Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs.

Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. Schooley RT, et al. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0115521. doi: 10.1128/AAC.01155-21. Epub 2021 Jul 26. Antimicrob Agents Chemother. 2021. PMID: 34310217 Free PMC article.

3

Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524).

Lo MK, Shrivastava-Ranjan P, Chatterjee P, Flint M, Beadle JR, Valiaeva N, Murphy J, Schooley RT, Hostetler KY, Montgomery JM, Spiropoulou CF. Lo MK, et al. Among authors: schooley rt. Microbiol Spectr. 2021 Dec 22;9(3):e0153721. doi: 10.1128/Spectrum.01537-21. Epub 2021 Nov 24. Microbiol Spectr. 2021. PMID: 34817209 Free PMC article.

4

Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate.

Beadle JR, Aldern KA, Zhang XQ, Valiaeva N, Hostetler KY, Schooley RT. Beadle JR, et al. Among authors: schooley rt. Antiviral Res. 2019 Nov;171:104614. doi: 10.1016/j.antiviral.2019.104614. Epub 2019 Sep 21. Antiviral Res. 2019. PMID: 31550449 Free PMC article.

5

Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication.

Valiaeva N, Wyles DL, Schooley RT, Hwu JB, Beadle JR, Prichard MN, Hostetler KY. Valiaeva N, et al. Among authors: schooley rt. Bioorg Med Chem. 2011 Aug 1;19(15):4616-25. doi: 10.1016/j.bmc.2011.06.009. Epub 2011 Jun 13. Bioorg Med Chem. 2011. PMID: 21719300 Free PMC article.

6

The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons.

Wyles DL, Kaihara KA, Korba BE, Schooley RT, Beadle JR, Hostetler KY. Wyles DL, et al. Among authors: schooley rt. Antimicrob Agents Chemother. 2009 Jun;53(6):2660-2. doi: 10.1128/AAC.01546-08. Epub 2009 Mar 16. Antimicrob Agents Chemother. 2009. PMID: 19289518 Free PMC article.

7

Temporal dynamics of inflammatory cytokines/chemokines during sofosbuvir and ribavirin therapy for genotype 2 and 3 hepatitis C infection.

Carlin AF, Aristizabal P, Song Q, Wang H, Paulson MS, Stamm LM, Schooley RT, Wyles DL. Carlin AF, et al. Among authors: schooley rt. Hepatology. 2015 Oct;62(4):1047-58. doi: 10.1002/hep.27971. Epub 2015 Aug 22. Hepatology. 2015. PMID: 26147061 Free PMC article.

8

Synergistic in vitro antiretroviral activity of a humanized monoclonal anti-CD4 antibody (TNX-355) and enfuvirtide (T-20).

Zhang XQ, Sorensen M, Fung M, Schooley RT. Zhang XQ, et al. Among authors: schooley rt. Antimicrob Agents Chemother. 2006 Jun;50(6):2231-3. doi: 10.1128/AAC.00761-05. Antimicrob Agents Chemother. 2006. PMID: 16723592 Free PMC article.

9

Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice.

Fowler AM, Tang WW, Young MP, Mamidi A, Viramontes KM, McCauley MD, Carlin AF, Schooley RT, Swanstrom J, Baric RS, Govero J, Diamond MS, Shresta S. Fowler AM, et al. Among authors: schooley rt. Cell Host Microbe. 2018 Nov 14;24(5):743-750.e5. doi: 10.1016/j.chom.2018.09.015. Cell Host Microbe. 2018. PMID: 30439343 Free PMC article.

10

Synergistic inhibition of hepatitis C virus infection by a novel microtubule inhibitor in combination with daclatasvir.

Zhang H, Zhang XQ, Huang LS, Fang X, Khan M, Xu Y, An J, Schooley RT, Huang Z. Zhang H, et al. Among authors: schooley rt. Biochem Biophys Rep. 2022 May 24;30:101283. doi: 10.1016/j.bbrep.2022.101283. eCollection 2022 Jul. Biochem Biophys Rep. 2022. PMID: 35647321 Free PMC article.

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