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Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, Presti RM, Mok CKP, Krammer F, Dai X, Ellebedy AH, Wu NC. Lei R, et al. Among authors: schmitz aj. Immunity. 2023 Nov 14;56(11):2621-2634.e6. doi: 10.1016/j.immuni.2023.10.005. Immunity. 2023. PMID: 37967533
Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, Krammer F, Ellebedy AH. Madsen A, et al. Among authors: schmitz aj. Immunity. 2020 Oct 13;53(4):852-863.e7. doi: 10.1016/j.immuni.2020.08.015. Epub 2020 Sep 24. Immunity. 2020. PMID: 32976769 Free PMC article.
Human germinal centres engage memory and naive B cells after influenza vaccination.
Turner JS, Zhou JQ, Han J, Schmitz AJ, Rizk AA, Alsoussi WB, Lei T, Amor M, McIntire KM, Meade P, Strohmeier S, Brent RI, Richey ST, Haile A, Yang YR, Klebert MK, Suessen T, Teefey S, Presti RM, Krammer F, Kleinstein SH, Ward AB, Ellebedy AH. Turner JS, et al. Among authors: schmitz aj. Nature. 2020 Oct;586(7827):127-132. doi: 10.1038/s41586-020-2711-0. Epub 2020 Aug 31. Nature. 2020. PMID: 32866963 Free PMC article.
A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Zhou JQ, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Altomare CG, Alsoussi WB, Case JB, VanBlargan LA, Lei T, Thapa M, Amanat F, Jeevan T, Fabrizio T, O'Halloran JA, Shi PY, Presti RM, Webby RJ, Krammer F, Whelan SPJ, Bajic G, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013. Epub 2021 Aug 17. Immunity. 2021. PMID: 34464596 Free PMC article.
Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreño-Parra JA, Jiménez-Alvarez L, Cruz-Lagunas A, Zúñiga J, Mudd PA, Cox RJ, Wilson IA, Ward AB, Ellebedy AH, Krammer F. Hansen L, et al. Among authors: schmitz aj. Immunity. 2023 Aug 8;56(8):1927-1938.e8. doi: 10.1016/j.immuni.2023.07.004. Epub 2023 Jul 27. Immunity. 2023. PMID: 37506693
SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses.
Turner JS, O'Halloran JA, Kalaidina E, Kim W, Schmitz AJ, Zhou JQ, Lei T, Thapa M, Chen RE, Case JB, Amanat F, Rauseo AM, Haile A, Xie X, Klebert MK, Suessen T, Middleton WD, Shi PY, Krammer F, Teefey SA, Diamond MS, Presti RM, Ellebedy AH. Turner JS, et al. Among authors: schmitz aj. Nature. 2021 Aug;596(7870):109-113. doi: 10.1038/s41586-021-03738-2. Epub 2021 Jun 28. Nature. 2021. PMID: 34182569 Free PMC article.
Germinal centre-driven maturation of B cell response to mRNA vaccination.
Kim W, Zhou JQ, Horvath SC, Schmitz AJ, Sturtz AJ, Lei T, Liu Z, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Whelan SPJ, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: schmitz aj. Nature. 2022 Apr;604(7904):141-145. doi: 10.1038/s41586-022-04527-1. Epub 2022 Feb 15. Nature. 2022. PMID: 35168246 Free PMC article.
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.
Chen RE, Zhang X, Case JB, Winkler ES, Liu Y, VanBlargan LA, Liu J, Errico JM, Xie X, Suryadevara N, Gilchuk P, Zost SJ, Tahan S, Droit L, Turner JS, Kim W, Schmitz AJ, Thapa M, Wang D, Boon ACM, Presti RM, O'Halloran JA, Kim AHJ, Deepak P, Pinto D, Fremont DH, Crowe JE Jr, Corti D, Virgin HW, Ellebedy AH, Shi PY, Diamond MS. Chen RE, et al. Among authors: schmitz aj. Nat Med. 2021 Apr;27(4):717-726. doi: 10.1038/s41591-021-01294-w. Epub 2021 Mar 4. Nat Med. 2021. PMID: 33664494 Free PMC article.
56 results