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882 results

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Rgs16 promotes antitumor CD8+ T cell exhaustion.
Weisshaar N, Wu J, Ming Y, Madi A, Hotz-Wagenblatt A, Ma S, Mieg A, Hering M, Zettl F, Mohr K, Schlimbach T, Ten Bosch N, Hertel F, Müller L, Byren H, Wang M, Borgers H, Munz M, Schmitt L, van der Hoeven F, Kloz U, Carretero R, Schleußner N, Jackstadt RF, Hofmann I, Cui G. Weisshaar N, et al. Among authors: schmitt l. Sci Immunol. 2022 May 27;7(71):eabh1873. doi: 10.1126/sciimmunol.abh1873. Epub 2022 May 27. Sci Immunol. 2022. PMID: 35622904
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila.
Port F, Strein C, Stricker M, Rauscher B, Heigwer F, Zhou J, Beyersdörffer C, Frei J, Hess A, Kern K, Lange L, Langner N, Malamud R, Pavlović B, Rädecke K, Schmitt L, Voos L, Valentini E, Boutros M. Port F, et al. Among authors: schmitt l. Elife. 2020 Feb 13;9:e53865. doi: 10.7554/eLife.53865. Elife. 2020. PMID: 32053108 Free PMC article.
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.
Gatzweiler C, Ridinger J, Herter S, Gerloff XF, ElHarouni D, Berker Y, Imle R, Schmitt L, Kreth S, Stainczyk S, Ayhan S, Najafi S, Krunic D, Frese K, Meder B, Reuss D, Fiesel P, Schramm K, Blattner-Johnson M, Jones DTW, Banito A, Westermann F, Oppermann S, Milde T, Peterziel H, Witt O, Oehme I. Gatzweiler C, et al. Among authors: schmitt l. Cancers (Basel). 2022 Feb 8;14(3):849. doi: 10.3390/cancers14030849. Cancers (Basel). 2022. PMID: 35159116 Free PMC article.
TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.
Kälin RE, Cai L, Li Y, Zhao D, Zhang H, Cheng J, Zhang W, Wu Y, Eisenhut K, Janssen P, Schmitt L, Enard W, Michels F, Flüh C, Hou M, Kirchleitner SV, Siller S, Schiemann M, Andrä I, Montanez E, Giachino C, Taylor V, Synowitz M, Tonn JC, von Baumgarten L, Schulz C, Hellmann I, Glass R. Kälin RE, et al. Among authors: schmitt l. Cell Syst. 2021 Mar 17;12(3):248-262.e7. doi: 10.1016/j.cels.2021.01.002. Epub 2021 Feb 15. Cell Syst. 2021. PMID: 33592194 Free article.
CRISPR/Cas9 as a tool to dissect cancer mutations.
Sayed S, Paszkowski-Rogacz M, Schmitt LT, Buchholz F. Sayed S, et al. Methods. 2019 Jul 15;164-165:36-48. doi: 10.1016/j.ymeth.2019.05.007. Epub 2019 May 10. Methods. 2019. PMID: 31078796 Free article.
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Sigaud R, Rösch L, Gatzweiler C, Benzel J, von Soosten L, Peterziel H, Selt F, Najafi S, Ayhan S, Gerloff XF, Hofmann N, Büdenbender I, Schmitt L, Foerster KI, Burhenne J, Haefeli WE, Korshunov A, Sahm F, van Tilburg CM, Jones DTW, Pfister SM, Knoerzer D, Kreider BL, Sauter M, Pajtler KW, Zuckermann M, Oehme I, Witt O, Milde T. Sigaud R, et al. Among authors: schmitt l. Neuro Oncol. 2023 Mar 14;25(3):566-579. doi: 10.1093/neuonc/noac183. Neuro Oncol. 2023. PMID: 35882450 Free PMC article.
882 results