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Selective targeting of tumor associated macrophages in different tumor models.
Kakoschky B, Pleli T, Schmithals C, Zeuzem S, Brüne B, Vogl TJ, Korf HW, Weigert A, Piiper A. Kakoschky B, et al. Among authors: schmithals c. PLoS One. 2018 Feb 15;13(2):e0193015. doi: 10.1371/journal.pone.0193015. eCollection 2018. PLoS One. 2018. PMID: 29447241 Free PMC article.
Reduced efficacy of the Plk1 inhibitor BI 2536 on the progression of hepatocellular carcinoma due to low intratumoral drug levels.
Haupenthal J, Bihrer V, Korkusuz H, Kollmar O, Schmithals C, Kriener S, Engels K, Pleli T, Benz A, Canamero M, Longerich T, Kronenberger B, Richter S, Waidmann O, Vogl TJ, Zeuzem S, Piiper A. Haupenthal J, et al. Among authors: schmithals c. Neoplasia. 2012 May;14(5):410-9. doi: 10.1596/neo.111366. Neoplasia. 2012. PMID: 22745587 Free PMC article.
Biodegradable human serum albumin nanoparticles as contrast agents for the detection of hepatocellular carcinoma by magnetic resonance imaging.
Watcharin W, Schmithals C, Pleli T, Köberle V, Korkusuz H, Huebner F, Zeuzem S, Korf HW, Vogl TJ, Rittmeyer C, Terfort A, Piiper A, Gelperina S, Kreuter J. Watcharin W, et al. Among authors: schmithals c. Eur J Pharm Biopharm. 2014 May;87(1):132-41. doi: 10.1016/j.ejpb.2013.12.010. Epub 2013 Dec 21. Eur J Pharm Biopharm. 2014. PMID: 24365328
Detection of hepatocellular carcinoma in transgenic mice by Gd-DTPA- and rhodamine 123-conjugated human serum albumin nanoparticles in T1 magnetic resonance imaging.
Watcharin W, Schmithals C, Pleli T, Köberle V, Korkusuz H, Hübner F, Waidmann O, Zeuzem S, Korf HW, Terfort A, Gelperina S, Vogl TJ, Kreuter J, Piiper A. Watcharin W, et al. Among authors: schmithals c. J Control Release. 2015 Feb 10;199:63-71. doi: 10.1016/j.jconrel.2014.11.023. Epub 2014 Dec 10. J Control Release. 2015. PMID: 25499552
Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition.
Ibrahim AA, Schmithals C, Kowarz E, Köberle V, Kakoschky B, Pleli T, Kollmar O, Nitsch S, Waidmann O, Finkelmeier F, Zeuzem S, Korf HW, Schmid T, Weigert A, Kronenberger B, Marschalek R, Piiper A. Ibrahim AA, et al. Among authors: schmithals c. Clin Cancer Res. 2017 Jul 15;23(14):3896-3905. doi: 10.1158/1078-0432.CCR-16-1762. Epub 2017 Feb 6. Clin Cancer Res. 2017. PMID: 28167508
Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis.
Waidmann O, Pleli T, Weigert A, Imelmann E, Kakoschky B, Schmithals C, Döring C, Frank M, Longerich T, Köberle V, Hansmann ML, Brüne B, Zeuzem S, Piiper A, Dikic I. Waidmann O, et al. Among authors: schmithals c. Sci Rep. 2020 Oct 1;10(1):16264. doi: 10.1038/s41598-020-73387-4. Sci Rep. 2020. PMID: 33004985 Free PMC article.
An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms.
Arencibia JM, Fröhner W, Krupa M, Pastor-Flores D, Merker P, Oellerich T, Neimanis S, Schmithals C, Köberle V, Süß E, Zeuzem S, Stark H, Piiper A, Odadzic D, Schulze JO, Biondi RM. Arencibia JM, et al. Among authors: schmithals c. ACS Chem Biol. 2017 Feb 17;12(2):564-573. doi: 10.1021/acschembio.6b00827. Epub 2017 Jan 13. ACS Chem Biol. 2017. PMID: 28045490
16 results