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B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Among authors: schmidt supprian m. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.
NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells.
Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, Nishikawa S, Rajewsky K, Schmidt-Supprian M. Sasaki Y, et al. Among authors: schmidt supprian m. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10883-8. doi: 10.1073/pnas.0805186105. Epub 2008 Jul 28. Proc Natl Acad Sci U S A. 2008. PMID: 18663224 Free PMC article.
Mature T cells depend on signaling through the IKK complex.
Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israël A, Rajewsky K, Pasparakis M. Schmidt-Supprian M, et al. Immunity. 2003 Sep;19(3):377-89. doi: 10.1016/s1074-7613(03)00237-1. Immunity. 2003. PMID: 14499113 Free article.
107 results