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Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, Schmidt NM, Amin OE, Gill US, Stegmann KA, Burton AR, Stephenson E, Reynolds G, Whelan M, Sanchez J, de Maeyer R, Thakker C, Suveizdyte K, Uddin I, Ortega-Prieto AM, Grant C, Froghi F, Fusai G, Lens S, Pérez-Del-Pulgar S, Al-Akkad W, Mazza G, Noursadeghi M, Akbar A, Kennedy PTF, Davidson BR, Prinz M, Chain BM, Haniffa M, Gilroy DW, Dorner M, Bengsch B, Schurich A, Maini MK. Pallett LJ, et al. Among authors: schmidt nm. Nature. 2023 Feb;614(7947):334-342. doi: 10.1038/s41586-022-05645-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697826
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
Easom NJW, Stegmann KA, Swadling L, Pallett LJ, Burton AR, Odera D, Schmidt N, Huang WC, Fusai G, Davidson B, Maini MK. Easom NJW, et al. Front Immunol. 2018 May 9;9:1009. doi: 10.3389/fimmu.2018.01009. eCollection 2018. Front Immunol. 2018. PMID: 29867983 Free PMC article.
T cell metabolism in chronic viral infection.
Pallett LJ, Schmidt N, Schurich A. Pallett LJ, et al. Clin Exp Immunol. 2019 Aug;197(2):143-152. doi: 10.1111/cei.13308. Epub 2019 May 20. Clin Exp Immunol. 2019. PMID: 31038727 Free PMC article. Review.
Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence.
Swadling L, Pallett LJ, Diniz MO, Baker JM, Amin OE, Stegmann KA, Burton AR, Schmidt NM, Jeffery-Smith A, Zakeri N, Suveizdyte K, Froghi F, Fusai G, Rosenberg WM, Davidson BR, Schurich A, Simon AK, Maini MK. Swadling L, et al. Among authors: schmidt nm. Cell Rep. 2020 Jan 21;30(3):687-698.e6. doi: 10.1016/j.celrep.2019.12.050. Cell Rep. 2020. PMID: 31968246 Free PMC article.
Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.
Pallett LJ, Burton AR, Amin OE, Rodriguez-Tajes S, Patel AA, Zakeri N, Jeffery-Smith A, Swadling L, Schmidt NM, Baiges A, Gander A, Yu D, Nasralla D, Froghi F, Iype S, Davidson BR, Thorburn D, Yona S, Forns X, Maini MK. Pallett LJ, et al. Among authors: schmidt nm. J Exp Med. 2020 Sep 7;217(9):e20200050. doi: 10.1084/jem.20200050. J Exp Med. 2020. PMID: 32602903 Free PMC article.
Cholesterol-modifying drugs in COVID-19.
Schmidt NM, Wing PAC, McKeating JA, Maini MK. Schmidt NM, et al. Oxf Open Immunol. 2020;1(1):iqaa001. doi: 10.1093/oxfimm/iqaa001. Epub 2020 Jun 18. Oxf Open Immunol. 2020. PMID: 33047740 Free PMC article.
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
Reynolds CJ, Swadling L, Gibbons JM, Pade C, Jensen MP, Diniz MO, Schmidt NM, Butler DK, Amin OE, Bailey SNL, Murray SM, Pieper FP, Taylor S, Jones J, Jones M, Lee WJ, Rosenheim J, Chandran A, Joy G, Di Genova C, Temperton N, Lambourne J, Cutino-Moguel T, Andiapen M, Fontana M, Smit A, Semper A, O'Brien B, Chain B, Brooks T, Manisty C, Treibel T, Moon JC; COVIDsortium investigators; Noursadeghi M; COVIDsortium immune correlates network; Altmann DM, Maini MK, McKnight Á, Boyton RJ. Reynolds CJ, et al. Among authors: schmidt nm. Sci Immunol. 2020 Dec 23;5(54):eabf3698. doi: 10.1126/sciimmunol.abf3698. Sci Immunol. 2020. PMID: 33361161 Free PMC article.
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Reynolds CJ, Pade C, Gibbons JM, Butler DK, Otter AD, Menacho K, Fontana M, Smit A, Sackville-West JE, Cutino-Moguel T, Maini MK, Chain B, Noursadeghi M; UK COVIDsortium Immune Correlates Network; Brooks T, Semper A, Manisty C, Treibel TA, Moon JC; UK COVIDsortium Investigators; Valdes AM, McKnight Á, Altmann DM, Boyton R. Reynolds CJ, et al. Science. 2021 Apr 30;372(6549):1418-23. doi: 10.1126/science.abh1282. Online ahead of print. Science. 2021. PMID: 33931567 Free PMC article.
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Schmidt NM, Wing PAC, Diniz MO, Pallett LJ, Swadling L, Harris JM, Burton AR, Jeffery-Smith A, Zakeri N, Amin OE, Kucykowicz S, Heemskerk MH, Davidson B, Meyer T, Grove J, Stauss HJ, Pineda-Torra I, Jolly C, Jury EC, McKeating JA, Maini MK. Schmidt NM, et al. Nat Commun. 2021 May 14;12(1):2814. doi: 10.1038/s41467-021-22967-7. Nat Commun. 2021. PMID: 33990561 Free PMC article.
Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study.
Gupta RK, Rosenheim J, Bell LC, Chandran A, Guerra-Assuncao JA, Pollara G, Whelan M, Artico J, Joy G, Kurdi H, Altmann DM, Boyton RJ, Maini MK, McKnight A, Lambourne J, Cutino-Moguel T, Manisty C, Treibel TA, Moon JC, Chain BM, Noursadeghi M; COVIDsortium Investigators. Gupta RK, et al. Lancet Microbe. 2021 Oct;2(10):e508-e517. doi: 10.1016/S2666-5247(21)00146-4. Epub 2021 Jul 6. Lancet Microbe. 2021. PMID: 34250515 Free PMC article.
143 results