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Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J. Sorrentino V, et al. Among authors: schmid aw. Nature. 2017 Dec 14;552(7684):187-193. doi: 10.1038/nature25143. Epub 2017 Dec 6. Nature. 2017. PMID: 29211722 Free PMC article.
Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregation.
Schmid AW, Condemi E, Tuchscherer G, Chiappe D, Mutter M, Vogel H, Moniatte M, Tsybin YO. Schmid AW, et al. J Biol Chem. 2011 Apr 8;286(14):12172-88. doi: 10.1074/jbc.M110.176149. Epub 2011 Feb 7. J Biol Chem. 2011. PMID: 21300794 Free PMC article.
Flagellar membranes are rich in raft-forming phospholipids.
Serricchio M, Schmid AW, Steinmann ME, Sigel E, Rauch M, Julkowska D, Bonnefoy S, Fort C, Bastin P, Bütikofer P. Serricchio M, et al. Among authors: schmid aw. Biol Open. 2015 Aug 14;4(9):1143-53. doi: 10.1242/bio.011957. Biol Open. 2015. PMID: 26276100 Free PMC article.
35 results