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Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.
Meinke PT, Colletti SL, Fisher MH, Wyvratt MJ, Shih TL, Ayer MB, Li C, Lim J, Ok D, Salva S, Warmke LM, Zakson M, Michael BF, Demontigny P, Ostlind DA, Fink D, Drag M, Schmatz DM, Shoop WL. Meinke PT, et al. Among authors: schmatz dm. J Med Chem. 2009 Jun 11;52(11):3505-15. doi: 10.1021/jm801334v. J Med Chem. 2009. PMID: 19445514
Nodulisporic acid side-chain modifications: access to the 2", 3", 4", and 6" registers.
Chakravarty PK, Shih TL, Colletti SL, Ayer MB, Snedden C, Kuo H, Tyagarajan S, Gregory L, Zakson-Aiken M, Shoop WL, Schmatz DM, Wyvratt M, Fisher MH, Meinke PT. Chakravarty PK, et al. Among authors: schmatz dm. Bioorg Med Chem Lett. 2003 Jan 6;13(1):147-50. doi: 10.1016/s0960-894x(02)00826-0. Bioorg Med Chem Lett. 2003. PMID: 12467636
Systemic efficacy of nodulisporamides against fleas on dogs.
Shoop WL, Zakson-Aiken M, Gregory LM, Michael BF, Pivnichny J, Meinke PT, Fisher MH, Wyvratt MJ, Pikounis B, Schmatz DM. Shoop WL, et al. Among authors: schmatz dm. J Parasitol. 2001 Oct;87(5):1150-4. doi: 10.1645/0022-3395(2001)087[1150:SEONAF]2.0.CO;2. J Parasitol. 2001. PMID: 11695382
Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles.
Berger R, Shoop WL, Pivnichny JV, Warmke LM, Zakson-Aiken M, Owens KA, deMontigny P, Schmatz DM, Wyvratt MJ, Fisher MH, Meinke PT, Colletti SL. Berger R, et al. Among authors: schmatz dm. Org Lett. 2001 Nov 15;3(23):3715-8. doi: 10.1021/ol016651x. Org Lett. 2001. PMID: 11700120
Synthesis and SAR studies of potent imidazopyridine anticoccidial agents.
Liang GB, Qian X, Feng D, Fisher M, Brown CM, Gurnett A, Leavitt PS, Liberator PA, Misura AS, Tamas T, Schmatz DM, Wyvratt M, Biftu T. Liang GB, et al. Among authors: schmatz dm. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3558-61. doi: 10.1016/j.bmcl.2007.04.041. Epub 2007 Apr 24. Bioorg Med Chem Lett. 2007. PMID: 17475489
Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.
Colletti SL, Frie JL, Dixon EC, Singh SB, Choi BK, Scapin G, Fitzgerald CE, Kumar S, Nichols EA, O'Keefe SJ, O'Neill EA, Porter G, Samuel K, Schmatz DM, Schwartz CD, Shoop WL, Thompson CM, Thompson JE, Wang R, Woods A, Zaller DM, Doherty JB. Colletti SL, et al. Among authors: schmatz dm. J Med Chem. 2003 Jan 30;46(3):349-52. doi: 10.1021/jm025585h. J Med Chem. 2003. PMID: 12540232
89 results