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Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer.
EMBO Mol Med. 2022 Oct 10;14(10):e15705. doi: 10.15252/emmm.202215705. Epub 2022 Aug 22.
EMBO Mol Med. 2022.
PMID: 35993110
Free PMC article.
Detecting drug resistance in pancreatic cancer organoids guides optimized chemotherapy treatment.
Hennig A, Baenke F, Klimova A, Drukewitz S, Jahnke B, Brückmann S, Secci R, Winter C, Schmäche T, Seidlitz T, Bereuter JP, Polster H, Eckhardt L, Schneider SA, Brückner S, Schmelz R, Babatz J, Kahlert C, Distler M, Hampe J, Reichert M, Zeißig S, Folprecht G, Weitz J, Aust D, Welsch T, Stange DE.
Hennig A, et al. Among authors: schmache t.
J Pathol. 2022 Aug;257(5):607-619. doi: 10.1002/path.5906. Epub 2022 May 5.
J Pathol. 2022.
PMID: 35373359
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A Novel Splice Variant of the Inhibitor of Growth 3 Lacks the Plant Homeodomain and Regulates Epithelial-Mesenchymal Transition in Prostate Cancer Cells.
Melekhova A, Leeder M, Pungsrinont T, Schmäche T, Kallenbach J, Ehsani M, Mirzakhani K, Rasa SMM, Neri F, Baniahmad A.
Melekhova A, et al. Among authors: schmache t.
Biomolecules. 2021 Aug 4;11(8):1152. doi: 10.3390/biom11081152.
Biomolecules. 2021.
PMID: 34439818
Free PMC article.
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Stratifying esophago-gastric cancer treatment using a patient-derived organoid-based threshold.
Schmäche T, Fohgrub J, Klimova A, Laaber K, Drukewitz S, Merboth F, Hennig A, Seidlitz T, Herbst F, Baenke F, Ada AM, Groß T, Wenzel C, Ball CR, Praetorius C, Schmidt T, Ringelband-Schilling B, Koschny R, Stenzinger A, Roeder I, Jaeger D, Zeissig S, Welsch T, Aust D, Glimm H, Folprecht G, Weitz J, Haag GM, Stange DE.
Schmäche T, et al.
Mol Cancer. 2024 Jan 10;23(1):10. doi: 10.1186/s12943-023-01919-3.
Mol Cancer. 2024.
PMID: 38200602
Free PMC article.
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CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability.
Mircetic J, Camgöz A, Abohawya M, Ding L, Dietzel J, Tobar SG, Paszkowski-Rogacz M, Seidlitz T, Schmäche T, Mehnert MC, Sidorova O, Weitz J, Buchholz F, Stange DE.
Mircetic J, et al. Among authors: schmache t.
Small Methods. 2023 Jun;7(6):e2201605. doi: 10.1002/smtd.202201605. Epub 2023 Mar 12.
Small Methods. 2023.
PMID: 36908010
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Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K, Lößner AJ, William D, Czempiel T, Beyreuther E, Klimova A, Lehmann C, Schmäche T, Merker SR, Naumann M, Ada AM, Baenke F, Seidlitz T, Bütof R, Dietrich A, Krause M, Weitz J, Klink B, von Neubeck C, Stange DE.
Pape K, et al. Among authors: schmache t.
Cancers (Basel). 2022 Oct 11;14(20):4984. doi: 10.3390/cancers14204984.
Cancers (Basel). 2022.
PMID: 36291768
Free PMC article.
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