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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles.
Madsen TD, Hansen LH, Hintze J, Ye Z, Jebari S, Andersen DB, Joshi HJ, Ju T, Goetze JP, Martin C, Rosenkilde MM, Holst JJ, Kuhre RE, Goth CK, Vakhrushev SY, Schjoldager KT. Madsen TD, et al. Among authors: schjoldager kt. Nat Commun. 2020 Aug 20;11(1):4033. doi: 10.1038/s41467-020-17473-1. Nat Commun. 2020. PMID: 32820167 Free PMC article.
Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor.
Hansen LH, Madsen TD, Goth CK, Clausen H, Chen Y, Dzhoyashvili N, Iyer SR, Sangaralingham SJ, Burnett JC Jr, Rehfeld JF, Vakhrushev SY, Schjoldager KT, Goetze JP. Hansen LH, et al. Among authors: schjoldager kt. J Biol Chem. 2019 Aug 23;294(34):12567-12578. doi: 10.1074/jbc.RA119.008102. Epub 2019 Jun 11. J Biol Chem. 2019. PMID: 31186350 Free PMC article.
SnapShot: O-Glycosylation Pathways across Kingdoms.
Joshi HJ, Narimatsu Y, Schjoldager KT, Tytgat HLP, Aebi M, Clausen H, Halim A. Joshi HJ, et al. Among authors: schjoldager kt. Cell. 2018 Jan 25;172(3):632-632.e2. doi: 10.1016/j.cell.2018.01.016. Cell. 2018. PMID: 29373833 Free article. Review.
Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions.
Wang S, Mao Y, Narimatsu Y, Ye Z, Tian W, Goth CK, Lira-Navarrete E, Pedersen NB, Benito-Vicente A, Martin C, Uribe KB, Hurtado-Guerrero R, Christoffersen C, Seidah NG, Nielsen R, Christensen EI, Hansen L, Bennett EP, Vakhrushev SY, Schjoldager KT, Clausen H. Wang S, et al. Among authors: schjoldager kt. J Biol Chem. 2018 May 11;293(19):7408-7422. doi: 10.1074/jbc.M117.817981. Epub 2018 Mar 20. J Biol Chem. 2018. PMID: 29559555 Free PMC article.
Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines.
Hintze J, Ye Z, Narimatsu Y, Madsen TD, Joshi HJ, Goth CK, Linstedt A, Bachert C, Mandel U, Bennett EP, Vakhrushev SY, Schjoldager KT. Hintze J, et al. Among authors: schjoldager kt. J Biol Chem. 2018 Dec 7;293(49):19064-19077. doi: 10.1074/jbc.RA118.004516. Epub 2018 Oct 16. J Biol Chem. 2018. PMID: 30327431 Free PMC article.
48 results