Schjerven H - Search Results

1

Ikaros is a principal regulator of Aire⁺ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance.

Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. Sin JH, et al. Among authors: schjerven h. Sci Immunol. 2023 Oct 27;8(88):eabq3109. doi: 10.1126/sciimmunol.abq3109. Epub 2023 Oct 27. Sci Immunol. 2023. PMID: 37889983

2

Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway.

Li S, Heller JJ, Bostick JW, Lee A, Schjerven H, Kastner P, Chan S, Chen ZE, Zhou L. Li S, et al. Among authors: schjerven h. Immunity. 2016 Jul 19;45(1):185-97. doi: 10.1016/j.immuni.2016.06.027. Immunity. 2016. PMID: 27438771 Free PMC article.

3

Ikaros Regulates microRNA Networks in Acute Lymphoblastic Leukemia.

Kogut S, Paculova H, Rodriguez P, Boyd J, Richman A, Palaria A, Schjerven H, Frietze S. Kogut S, et al. Among authors: schjerven h. Epigenomes. 2022 Oct 19;6(4):37. doi: 10.3390/epigenomes6040037. Epigenomes. 2022. PMID: 36278683 Free PMC article.

4

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.

Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST. Schjerven H, et al. Nat Immunol. 2013 Oct;14(10):1073-83. doi: 10.1038/ni.2707. Epub 2013 Sep 8. Nat Immunol. 2013. PMID: 24013668 Free PMC article.

5

A kindred with mutant IKAROS and autoimmunity.

Van Nieuwenhove E, Garcia-Perez JE, Helsen C, Rodriguez PD, van Schouwenburg PA, Dooley J, Schlenner S, van der Burg M, Verhoeyen E, Gijsbers R, Frietze S, Schjerven H, Meyts I, Claessens F, Humblet-Baron S, Wouters C, Liston A. Van Nieuwenhove E, et al. Among authors: schjerven h. J Allergy Clin Immunol. 2018 Aug;142(2):699-702.e12. doi: 10.1016/j.jaci.2018.04.008. Epub 2018 Apr 27. J Allergy Clin Immunol. 2018. PMID: 29705243 Free PMC article.

6

Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros.

Heller JJ, Schjerven H, Li S, Lee A, Qiu J, Chen ZM, Smale ST, Zhou L. Heller JJ, et al. Among authors: schjerven h. J Immunol. 2014 Oct 15;193(8):3934-46. doi: 10.4049/jimmunol.1401234. Epub 2014 Sep 5. J Immunol. 2014. PMID: 25194055 Free PMC article.

7

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.

Song C, Gowda C, Pan X, Ding Y, Tong Y, Tan BH, Wang H, Muthusami S, Ge Z, Sachdev M, Amin SG, Desai D, Gowda K, Gowda R, Robertson GP, Schjerven H, Muschen M, Payne KJ, Dovat S. Song C, et al. Among authors: schjerven h. Blood. 2015 Oct 8;126(15):1813-22. doi: 10.1182/blood-2015-06-651505. Epub 2015 Jul 28. Blood. 2015. PMID: 26219304 Free PMC article.

8

Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.

Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, Müschen M, Kornblau SM, Farrar MA. Katerndahl CDS, et al. Among authors: schjerven h. Nat Immunol. 2017 Jun;18(6):694-704. doi: 10.1038/ni.3716. Epub 2017 Apr 3. Nat Immunol. 2017. PMID: 28369050 Free PMC article.

9

Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1⁺ pre-B ALL.

Schjerven H, Ayongaba EF, Aghajanirefah A, McLaughlin J, Cheng D, Geng H, Boyd JR, Eggesbø LM, Lindeman I, Heath JL, Park E, Witte ON, Smale ST, Frietze S, Müschen M. Schjerven H, et al. J Exp Med. 2017 Mar 6;214(3):793-814. doi: 10.1084/jem.20160049. Epub 2017 Feb 11. J Exp Med. 2017. PMID: 28190001 Free PMC article.

10

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.

Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. Reynaud D, et al. Among authors: schjerven h. Nat Immunol. 2008 Aug;9(8):927-36. doi: 10.1038/ni.1626. Epub 2008 Jun 22. Nat Immunol. 2008. PMID: 18568028 Free PMC article.

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