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Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis.
Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. Pröbstel AK, et al. Among authors: schirmer l. Sci Immunol. 2020 Nov 20;5(53):eabc7191. doi: 10.1126/sciimmunol.abc7191. Sci Immunol. 2020. PMID: 33219152 Free PMC article.
Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions.
Schirmer L, Srivastava R, Kalluri SR, Böttinger S, Herwerth M, Carassiti D, Srivastava B, Gempt J, Schlegel J, Kuhlmann T, Korn T, Reynolds R, Hemmer B. Schirmer L, et al. Ann Neurol. 2014 Jun;75(6):810-28. doi: 10.1002/ana.24168. Epub 2014 May 21. Ann Neurol. 2014. PMID: 24777949
Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.
Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH. Schirmer L, et al. Elife. 2018 Sep 11;7:e36428. doi: 10.7554/eLife.36428. Elife. 2018. PMID: 30204081 Free PMC article.
Neuronal vulnerability and multilineage diversity in multiple sclerosis.
Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH. Schirmer L, et al. Nature. 2019 Sep;573(7772):75-82. doi: 10.1038/s41586-019-1404-z. Epub 2019 Jul 17. Nature. 2019. PMID: 31316211 Free PMC article.
Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology.
Deigendesch N, Sironi L, Kutza M, Wischnewski S, Fuchs V, Hench J, Frank A, Nienhold R, Mertz KD, Cathomas G, Matter MS, Siegemund M, Tolnay M, Schirmer L, Pröbstel AK, Tzankov A, Frank S. Deigendesch N, et al. Among authors: schirmer l. Acta Neuropathol. 2020 Oct;140(4):583-586. doi: 10.1007/s00401-020-02213-y. Epub 2020 Aug 26. Acta Neuropathol. 2020. PMID: 32851506 Free PMC article. No abstract available.
Cortical projection neurons as a therapeutic target in multiple sclerosis.
Beutel T, Dzimiera J, Kapell H, Engelhardt M, Gass A, Schirmer L. Beutel T, et al. Among authors: schirmer l. Expert Opin Ther Targets. 2020 Dec;24(12):1211-1224. doi: 10.1080/14728222.2020.1842358. Epub 2020 Nov 8. Expert Opin Ther Targets. 2020. PMID: 33103501 Review.
Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis.
Kim K, Pröbstel AK, Baumann R, Dyckow J, Landefeld J, Kogl E, Madireddy L, Loudermilk R, Eggers EL, Singh S, Caillier SJ, Hauser SL, Cree BAC; UCSF MS-EPIC Team; Schirmer L, Wilson MR, Baranzini SE. Kim K, et al. Among authors: schirmer l. Brain. 2021 Mar 3;144(2):450-461. doi: 10.1093/brain/awaa421. Brain. 2021. PMID: 33374005 Free PMC article.
100 results