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P-glycoprotein acts as an immunomodulator during neuroinflammation.
Kooij G, Backer R, Koning JJ, Reijerkerk A, van Horssen J, van der Pol SM, Drexhage J, Schinkel A, Dijkstra CD, den Haan JM, Geijtenbeek TB, de Vries HE. Kooij G, et al. Among authors: schinkel a. PLoS One. 2009 Dec 8;4(12):e8212. doi: 10.1371/journal.pone.0008212. PLoS One. 2009. PMID: 19997559 Free PMC article.
Peripheral neuropathy in mice transgenic for a human MDR3 P-glycoprotein mini-gene.
Smit JJ, Baas F, Hoogendijk JE, Jansen GH, van der Valk MA, Schinkel AH, Berns AJ, Acton D, Nooter K, Burger H, Smith SJ, Borst P. Smit JJ, et al. Among authors: schinkel ah. J Neurosci. 1996 Oct 15;16(20):6386-93. doi: 10.1523/JNEUROSCI.16-20-06386.1996. J Neurosci. 1996. PMID: 8815917 Free PMC article.
Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.
van Waterschoot RA, Lagas JS, Wagenaar E, van der Kruijssen CM, van Herwaarden AE, Song JY, Rooswinkel RW, van Tellingen O, Rosing H, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: schinkel ah. Cancer Res. 2009 Dec 1;69(23):8996-9002. doi: 10.1158/0008-5472.CAN-09-2915. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920203 Free article.
534 results