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Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.
Lisco A, Vanpouille C, Tchesnokov EP, Grivel JC, Biancotto A, Brichacek B, Elliott J, Fromentin E, Shattock R, Anton P, Gorelick R, Balzarini J, McGuigan C, Derudas M, Götte M, Schinazi RF, Margolis L. Lisco A, et al. Among authors: schinazi rf. Cell Host Microbe. 2008 Sep 11;4(3):260-270. doi: 10.1016/j.chom.2008.07.008. Cell Host Microbe. 2008. PMID: 18779052 Free PMC article.
Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.
van Maarseveen NM, Wensing AM, de Jong D, Beilhartz GL, Obikhod A, Tao S, Pingen M, Arends JE, Hoepelman AI, Schinazi RF, Götte M, Nijhuis M. van Maarseveen NM, et al. Among authors: schinazi rf. Antivir Ther. 2011;16(7):1123-30. doi: 10.3851/IMP1912. Antivir Ther. 2011. PMID: 22024528 Free PMC article.
A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin.
Kulkarni AS, Damha MJ, Schinazi RF, Mo H, Doehle B, Sagan SM, Götte M. Kulkarni AS, et al. Among authors: schinazi rf. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2018-27. doi: 10.1128/AAC.02436-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26824949 Free PMC article.
Structural and Antiviral Studies of the Human Norovirus GII.4 Protease.
Muzzarelli KM, Kuiper B, Spellmon N, Brunzelle J, Hackett J, Amblard F, Zhou S, Liu P, Kovari IA, Yang Z, Schinazi RF, Kovari LC. Muzzarelli KM, et al. Among authors: schinazi rf. Biochemistry. 2019 Feb 19;58(7):900-907. doi: 10.1021/acs.biochem.8b01063. Epub 2019 Jan 16. Biochemistry. 2019. PMID: 30605321 Free PMC article.
Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template.
Gordon CJ, Tchesnokov EP, Schinazi RF, Götte M. Gordon CJ, et al. Among authors: schinazi rf. J Biol Chem. 2021 Jul;297(1):100770. doi: 10.1016/j.jbc.2021.100770. Epub 2021 May 11. J Biol Chem. 2021. PMID: 33989635 Free PMC article.
606 results