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A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde MT, Cupovic J, Palmowski YA, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou MT, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger KK, Bald T, Schietinger A, Schürch C, Ring SS, Flatz L. Purde MT, et al. Among authors: schietinger a. Mol Ther. 2024 Feb 7;32(2):426-439. doi: 10.1016/j.ymthe.2023.11.026. Epub 2023 Dec 5. Mol Ther. 2024. PMID: 38058126 Free article.
GABA Regulates Electrical Activity and Tumor Initiation in Melanoma.
Tagore M, Hergenreder E, Perlee SC, Cruz NM, Menocal L, Suresh S, Chan E, Baron M, Melendez S, Dave A, Chatila WK, Nsengimana J, Koche RP, Hollmann TJ, Ideker T, Studer L, Schietinger A, White RM. Tagore M, et al. Among authors: schietinger a. Cancer Discov. 2023 Oct 5;13(10):2270-2291. doi: 10.1158/2159-8290.CD-23-0389. Cancer Discov. 2023. PMID: 37553760 Free PMC article.
Ovarian cancer mutational processes drive site-specific immune evasion.
Vázquez-García I, Uhlitz F, Ceglia N, Lim JLP, Wu M, Mohibullah N, Niyazov J, Ruiz AEB, Boehm KM, Bojilova V, Fong CJ, Funnell T, Grewal D, Havasov E, Leung S, Pasha A, Patel DM, Pourmaleki M, Rusk N, Shi H, Vanguri R, Williams MJ, Zhang AW, Broach V, Chi DS, Da Cruz Paula A, Gardner GJ, Kim SH, Lennon M, Long Roche K, Sonoda Y, Zivanovic O, Kundra R, Viale A, Derakhshan FN, Geneslaw L, Issa Bhaloo S, Maroldi A, Nunez R, Pareja F, Stylianou A, Vahdatinia M, Bykov Y, Grisham RN, Liu YL, Lakhman Y, Nikolovski I, Kelly D, Gao J, Schietinger A, Hollmann TJ, Bakhoum SF, Soslow RA, Ellenson LH, Abu-Rustum NR, Aghajanian C, Friedman CF, McPherson A, Weigelt B, Zamarin D, Shah SP. Vázquez-García I, et al. Among authors: schietinger a. Nature. 2022 Dec;612(7941):778-786. doi: 10.1038/s41586-022-05496-1. Epub 2022 Dec 14. Nature. 2022. PMID: 36517593 Free PMC article.
Turbocharging the T Cell to Fight Cancer.
Schietinger A. Schietinger A. N Engl J Med. 2022 Jun 16;386(24):2334-2336. doi: 10.1056/NEJMcibr2203616. Epub 2022 Jun 1. N Engl J Med. 2022. PMID: 35648702 No abstract available.
Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging.
Tee SS, Kim N, Cullen Q, Eskandari R, Mamakhanyan A, Srouji RM, Chirayil R, Jeong S, Shakiba M, Kastenhuber ER, Chen S, Sigel C, Lowe SW, Jarnagin WR, Thompson CB, Schietinger A, Keshari KR. Tee SS, et al. Among authors: schietinger a. Sci Adv. 2022 Apr 8;8(14):eabm7985. doi: 10.1126/sciadv.abm7985. Epub 2022 Apr 6. Sci Adv. 2022. PMID: 35385296 Free PMC article.
Noninvasive Imaging of CD4+ T Cells in Humanized Mice.
Nagle VL, Hertz CAJ, Henry KE, Graham MS, Campos C, Pillarsetty N, Schietinger A, Mellinghoff IK, Lewis JS. Nagle VL, et al. Among authors: schietinger a. Mol Cancer Ther. 2022 Apr 1;21(4):658-666. doi: 10.1158/1535-7163.MCT-21-0888. Mol Cancer Ther. 2022. PMID: 35131877 Free PMC article.
Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma.
Pourmaleki M, Jones CJ, Ariyan CE, Zeng Z, Pirun M, Navarrete DA, Li Y, Zhang M, Nandakumar S, Campos C, Nadeem S, Klimstra DS, Temple-Oberle CF, Brenn T, Lipson EJ, Schenk KM, Stein JE, Taube JM, White MG, Traweek R, Wargo JA, Kirkwood JM, Gasmi B, Goff SL, Corwin AD, McDonough E, Ginty F, Callahan MK, Schietinger A, Socci ND, Mellinghoff IK, Hollmann TJ. Pourmaleki M, et al. Among authors: schietinger a. Cancer Immunol Res. 2022 Mar 1;10(3):303-313. doi: 10.1158/2326-6066.CIR-21-1083. Cancer Immunol Res. 2022. PMID: 35013003 Free PMC article.
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion.
Shakiba M, Zumbo P, Espinosa-Carrasco G, Menocal L, Dündar F, Carson SE, Bruno EM, Sanchez-Rivera FJ, Lowe SW, Camara S, Koche RP, Reuter VP, Socci ND, Whitlock B, Tamzalit F, Huse M, Hellmann MD, Wells DK, Defranoux NA, Betel D, Philip M, Schietinger A. Shakiba M, et al. Among authors: schietinger a. J Exp Med. 2022 Feb 7;219(2):e20201966. doi: 10.1084/jem.20201966. Epub 2021 Dec 22. J Exp Med. 2022. PMID: 34935874 Free PMC article.
An autoimmune stem-like CD8 T cell population drives type 1 diabetes.
Gearty SV, Dündar F, Zumbo P, Espinosa-Carrasco G, Shakiba M, Sanchez-Rivera FJ, Socci ND, Trivedi P, Lowe SW, Lauer P, Mohibullah N, Viale A, DiLorenzo TP, Betel D, Schietinger A. Gearty SV, et al. Among authors: schietinger a. Nature. 2022 Feb;602(7895):156-161. doi: 10.1038/s41586-021-04248-x. Epub 2021 Nov 30. Nature. 2022. PMID: 34847567 Free PMC article.
42 results