Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

21 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.
Lillich FF, Willems S, Ni X, Kilu W, Borkowsky C, Brodsky M, Kramer JS, Brunst S, Hernandez-Olmos V, Heering J, Schierle S, Kestner RI, Mayser FM, Helmstädter M, Göbel T, Weizel L, Namgaladze D, Kaiser A, Steinhilber D, Pfeilschifter W, Kahnt AS, Proschak A, Chaikuad A, Knapp S, Merk D, Proschak E. Lillich FF, et al. Among authors: schierle s. J Med Chem. 2021 Dec 9;64(23):17259-17276. doi: 10.1021/acs.jmedchem.1c01331. Epub 2021 Nov 24. J Med Chem. 2021. PMID: 34818007
Development and in vitro Profiling of Dual FXR/LTA4H Modulators.
Schierle S, Brunst S, Helmstädter M, Ebert R, Kramer JS, Steinhilber D, Proschak E, Merk D. Schierle S, et al. ChemMedChem. 2021 Aug 5;16(15):2366-2374. doi: 10.1002/cmdc.202100118. Epub 2021 May 24. ChemMedChem. 2021. PMID: 33856122 Free PMC article.
A New FXR Ligand Chemotype with Agonist/Antagonist Switch.
Helmstädter M, Vietor J, Sommer J, Schierle S, Willems S, Kaiser A, Schmidt J, Merk D. Helmstädter M, et al. Among authors: schierle s. ACS Med Chem Lett. 2021 Feb 1;12(2):267-274. doi: 10.1021/acsmedchemlett.0c00647. eCollection 2021 Feb 11. ACS Med Chem Lett. 2021. PMID: 33603974 Free PMC article.
A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode.
Hanke T, Cheung SY, Kilu W, Heering J, Ni X, Planz V, Schierle S, Faudone G, Friedrich M, Wanior M, Werz O, Windbergs M, Proschak E, Schubert-Zsilavecz M, Chaikuad A, Knapp S, Merk D. Hanke T, et al. Among authors: schierle s. J Med Chem. 2020 May 14;63(9):4555-4561. doi: 10.1021/acs.jmedchem.9b01786. Epub 2020 Apr 20. J Med Chem. 2020. PMID: 32267688
21 results