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Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen.
Toda M, Reese G, Gadermaier G, Schulten V, Lauer I, Egger M, Briza P, Randow S, Wolfheimer S, Kigongo V, Del Mar San Miguel Moncin M, Fötisch K, Bohle B, Vieths S, Scheurer S. Toda M, et al. Among authors: scheurer s. J Allergy Clin Immunol. 2011 Nov;128(5):1022-30.e1-7. doi: 10.1016/j.jaci.2011.04.020. Epub 2011 May 14. J Allergy Clin Immunol. 2011. PMID: 21571358
Prevention of intestinal allergy in mice by rflaA:Ova is associated with enforced antigen processing and TLR5-dependent IL-10 secretion by mDC.
Schülke S, Wolfheimer S, Gadermaier G, Wangorsch A, Siebeneicher S, Briza P, Spreitzer I, Schiller D, Loeschner B, Uematsu S, Ryffel B, Akira S, Waibler Z, Vieths S, Toda M, Scheurer S. Schülke S, et al. Among authors: scheurer s. PLoS One. 2014 Feb 7;9(2):e87822. doi: 10.1371/journal.pone.0087822. eCollection 2014. PLoS One. 2014. PMID: 24516564 Free PMC article.
What makes an allergen?
Scheurer S, Toda M, Vieths S. Scheurer S, et al. Clin Exp Allergy. 2015 Jul;45(7):1150-61. doi: 10.1111/cea.12571. Clin Exp Allergy. 2015. PMID: 25989479 Review.
145 results