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Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome.
Friedman G, Levi-Galibov O, David E, Bornstein C, Giladi A, Dadiani M, Mayo A, Halperin C, Pevsner-Fischer M, Lavon H, Mayer S, Nevo R, Stein Y, Balint-Lahat N, Barshack I, Ali HR, Caldas C, Nili-Gal-Yam E, Alon U, Amit I, Scherz-Shouval R. Friedman G, et al. Nat Cancer. 2020 Jul;1(7):692-708. doi: 10.1038/s43018-020-0082-y. Epub 2020 Jun 29. Nat Cancer. 2020. PMID: 35122040
A framework for advancing our understanding of cancer-associated fibroblasts.
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. Sahai E, et al. Nat Rev Cancer. 2020 Mar;20(3):174-186. doi: 10.1038/s41568-019-0238-1. Epub 2020 Jan 24. Nat Rev Cancer. 2020. PMID: 31980749 Free PMC article. Review.
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer.
Levi-Galibov O, Lavon H, Wassermann-Dozorets R, Pevsner-Fischer M, Mayer S, Wershof E, Stein Y, Brown LE, Zhang W, Friedman G, Nevo R, Golani O, Katz LH, Yaeger R, Laish I, Porco JA, Sahai E, Shouval DS, Kelsen D, Scherz-Shouval R. Levi-Galibov O, et al. Nat Commun. 2020 Dec 7;11(1):6245. doi: 10.1038/s41467-020-20054-x. Nat Commun. 2020. PMID: 33288768 Free PMC article.
Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.
Grunberg N, Pevsner-Fischer M, Goshen-Lago T, Diment J, Stein Y, Lavon H, Mayer S, Levi-Galibov O, Friedman G, Ofir-Birin Y, Syu LJ, Migliore C, Shimoni E, Stemmer SM, Brenner B, Dlugosz AA, Lyden D, Regev-Rudzki N, Ben-Aharon I, Scherz-Shouval R. Grunberg N, et al. Cancer Res. 2021 Apr 1;81(7):1639-1653. doi: 10.1158/0008-5472.CAN-20-2756. Epub 2021 Feb 5. Cancer Res. 2021. PMID: 33547159 Free PMC article.
Cancer-associated fibroblasts in the single-cell era.
Lavie D, Ben-Shmuel A, Erez N, Scherz-Shouval R. Lavie D, et al. Nat Cancer. 2022 Jul;3(7):793-807. doi: 10.1038/s43018-022-00411-z. Epub 2022 Jul 26. Nat Cancer. 2022. PMID: 35883004 Free PMC article. Review.
46 results