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Novel MITF targets identified using a two-step DNA microarray strategy.
Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R, Steingrimsson E. Hoek KS, et al. Among authors: schepsky a. Pigment Cell Melanoma Res. 2008 Dec;21(6):665-76. doi: 10.1111/j.1755-148X.2008.00505.x. Pigment Cell Melanoma Res. 2008. PMID: 19067971
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue.
Bauer GL, Praetorius C, Bergsteinsdóttir K, Hallsson JH, Gísladóttir BK, Schepsky A, Swing DA, O'Sullivan TN, Arnheiter H, Bismuth K, Debbache J, Fletcher C, Warming S, Copeland NG, Jenkins NA, Steingrímsson E. Bauer GL, et al. Among authors: schepsky a. Genetics. 2009 Oct;183(2):581-94. doi: 10.1534/genetics.109.103945. Epub 2009 Jul 27. Genetics. 2009. PMID: 19635938 Free PMC article.
Subcellular localization and stability of MITF are modulated by the bHLH-Zip domain.
Fock V, Gudmundsson SR, Gunnlaugsson HO, Stefansson JA, Ionasz V, Schepsky A, Viarigi J, Reynisson IE, Pogenberg V, Wilmanns M, Ogmundsdottir MH, Steingrimsson E. Fock V, et al. Among authors: schepsky a. Pigment Cell Melanoma Res. 2019 Jan;32(1):41-54. doi: 10.1111/pcmr.12721. Epub 2018 Jul 20. Pigment Cell Melanoma Res. 2019. PMID: 29938923 Free PMC article.
Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.
Louphrasitthiphol P, Siddaway R, Loffreda A, Pogenberg V, Friedrichsen H, Schepsky A, Zeng Z, Lu M, Strub T, Freter R, Lisle R, Suer E, Thomas B, Schuster-Böckler B, Filippakopoulos P, Middleton M, Lu X, Patton EE, Davidson I, Lambert JP, Wilmanns M, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Among authors: schepsky a. Mol Cell. 2020 Aug 6;79(3):472-487.e10. doi: 10.1016/j.molcel.2020.05.025. Epub 2020 Jun 11. Mol Cell. 2020. PMID: 32531202 Free PMC article.
Acetylation reprograms MITF target selectivity and residence time.
Louphrasitthiphol P, Loffreda A, Pogenberg V, Picaud S, Schepsky A, Friedrichsen H, Zeng Z, Lashgari A, Thomas B, Patton EE, Wilmanns M, Filippakopoulos P, Lambert JP, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Among authors: schepsky a. Nat Commun. 2023 Sep 28;14(1):6051. doi: 10.1038/s41467-023-41793-7. Nat Commun. 2023. PMID: 37770430 Free PMC article.
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