Schepmann D - Search Results

1

Correction to "Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease".

Turgutalp B, Bhattarai P, Ercetin T, Luise C, Reis R, Gurdal EE, Isaak A, Biriken D, Dinter E, Sipahi H, Schepmann D, Junker A, Wünsch B, Sippl W, Gulcan HO, Kizil C, Yarim M. Turgutalp B, et al. Among authors: schepmann d. J Med Chem. 2023 Jan 26;66(2):1652. doi: 10.1021/acs.jmedchem.2c02094. Epub 2023 Jan 18. J Med Chem. 2023. PMID: 36651752 No abstract available.

2

Synthesis and NMDA-receptor affinity of 4-oxo-dexoxadrol derivatives.

Sax M, Ebert K, Schepmann D, Wibbeling B, Wünsch B. Sax M, et al. Among authors: schepmann d. Bioorg Med Chem. 2006 Sep 1;14(17):5955-62. doi: 10.1016/j.bmc.2006.05.020. Epub 2006 Jun 5. Bioorg Med Chem. 2006. PMID: 16750371

3

Synthesis of bicyclic sigma receptor ligands with cytotoxic activity.

Geiger C, Zelenka C, Weigl M, Fröhlich R, Wibbeling B, Lehmkuhl K, Schepmann D, Grünert R, Bednarski PJ, Wünsch B. Geiger C, et al. Among authors: schepmann d. J Med Chem. 2007 Nov 29;50(24):6144-53. doi: 10.1021/jm070620b. Epub 2007 Oct 30. J Med Chem. 2007. PMID: 17967001

4

Synthesis and structure-affinity relationships of novel spirocyclic sigma receptor ligands with furopyrazole structure.

Schläger T, Schepmann D, Würthwein EU, Wünsch B. Schläger T, et al. Among authors: schepmann d. Bioorg Med Chem. 2008 Mar 15;16(6):2992-3001. doi: 10.1016/j.bmc.2007.12.045. Epub 2007 Dec 25. Bioorg Med Chem. 2008. PMID: 18221879

5

Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety.

Jung B, Englberger W, Fröhlich R, Schepmann D, Lehmkuhl K, Wünsch B. Jung B, et al. Among authors: schepmann d. Bioorg Med Chem. 2008 Mar 15;16(6):2870-85. doi: 10.1016/j.bmc.2008.01.004. Epub 2008 Jan 10. Bioorg Med Chem. 2008. PMID: 18249546

6

Thiophene bioisosteres of spirocyclic sigma receptor ligands. 1. N-substituted spiro[piperidine-4,4'-thieno[3,2-c]pyrans].

Oberdorf C, Schepmann D, Vela JM, Diaz JL, Holenz J, Wünsch B. Oberdorf C, et al. Among authors: schepmann d. J Med Chem. 2008 Oct 23;51(20):6531-7. doi: 10.1021/jm8007739. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816044

7

Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity.

Holl R, Schepmann D, Grünert R, Bednarski PJ, Wünsch B. Holl R, et al. Among authors: schepmann d. Bioorg Med Chem. 2009 Jan 15;17(2):777-93. doi: 10.1016/j.bmc.2008.11.043. Epub 2008 Nov 24. Bioorg Med Chem. 2009. PMID: 19081725

8

Relationships between the structure of 6-substituted 6,8-diazabicyclo[3.2.2]nonan-2-ones and their sigma receptor affinity and cytotoxic activity.

Holl R, Schepmann D, Bednarski PJ, Grünert R, Wünsch B. Holl R, et al. Among authors: schepmann d. Bioorg Med Chem. 2009 Feb 15;17(4):1445-55. doi: 10.1016/j.bmc.2009.01.012. Epub 2009 Jan 15. Bioorg Med Chem. 2009. PMID: 19196515

9

Dancing of the second aromatic residue around the 6,8-diazabicyclo[3.2.2]nonane framework: influence on sigma receptor affinity and cytotoxicity.

Holl R, Schepmann D, Fröhlich R, Grünert R, Bednarski PJ, Wünsch B. Holl R, et al. Among authors: schepmann d. J Med Chem. 2009 Apr 9;52(7):2126-37. doi: 10.1021/jm801522j. J Med Chem. 2009. PMID: 19243173

10

Asymmetric synthesis of enantiomerically pure 2-substituted tetrahydro-3-benzazepines and their affinity to sigma1 receptors.

Husain SM, Fröhlich R, Schepmann D, Wünsch B. Husain SM, et al. Among authors: schepmann d. J Org Chem. 2009 Apr 3;74(7):2788-93. doi: 10.1021/jo900087e. J Org Chem. 2009. PMID: 19267485

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