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Page 1
Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification.
Kolli SK, Molina-Cruz A, Araki T, Geurten FJA, Ramesar J, Chevalley-Maurel S, Kroeze HJ, Bezemer S, de Korne C, Withers R, Raytselis N, El Hebieshy AF, Kim RQ, Child MA, Kakuta S, Hisaeda H, Kobayashi H, Annoura T, Hensbergen PJ, Franke-Fayard BM, Barillas-Mury C, Scheeren FA, Janse CJ. Kolli SK, et al. Among authors: scheeren fa. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2209729119. doi: 10.1073/pnas.2209729119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994647 Free PMC article.
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.
Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN. Logtenberg MEW, et al. Among authors: scheeren fa. Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833751 Free PMC article.
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.
Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PØ, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. Willingham SB, et al. Among authors: scheeren fa. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. doi: 10.1073/pnas.1121623109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451913 Free PMC article.
Identification of HLA-E Binding Mycobacterium tuberculosis-Derived Epitopes through Improved Prediction Models.
Ruibal P, Franken KLMC, van Meijgaarden KE, van Wolfswinkel M, Derksen I, Scheeren FA, Janssen GMC, van Veelen PA, Sarfas C, White AD, Sharpe SA, Palmieri F, Petrone L, Goletti D, Abeel T, Ottenhoff THM, Joosten SA. Ruibal P, et al. Among authors: scheeren fa. J Immunol. 2022 Oct 15;209(8):1555-1565. doi: 10.4049/jimmunol.2200122. Epub 2022 Sep 12. J Immunol. 2022. PMID: 36096642 Free PMC article.
Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming.
Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T. Kwakkenbos MJ, et al. Among authors: scheeren fa. Nat Med. 2010 Jan;16(1):123-8. doi: 10.1038/nm.2071. Epub 2009 Dec 20. Nat Med. 2010. PMID: 20023635 Free PMC article.
SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.
Mezzadra R, de Bruijn M, Jae LT, Gomez-Eerland R, Duursma A, Scheeren FA, Brummelkamp TR, Schumacher TN. Mezzadra R, et al. Among authors: scheeren fa. PLoS One. 2019 Feb 12;14(2):e0212053. doi: 10.1371/journal.pone.0212053. eCollection 2019. PLoS One. 2019. PMID: 30753225 Free PMC article.
54 results