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Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.
Glicksberg BS, Amadori L, Akers NK, Sukhavasi K, Franzén O, Li L, Belbin GM, Ayers KL, Shameer K, Badgeley MA, Johnson KW, Readhead B, Darrow BJ, Kenny EE, Betsholtz C, Ermel R, Skogsberg J, Ruusalepp A, Schadt EE, Dudley JT, Ren H, Kovacic JC, Giannarelli C, Li SD, Björkegren JLM, Chen R. Glicksberg BS, et al. Among authors: schadt ee. BMC Med Genomics. 2019 Jul 25;12(Suppl 6):108. doi: 10.1186/s12920-019-0542-3. BMC Med Genomics. 2019. PMID: 31345219 Free PMC article.
Coanalysis of GWAS with eQTLs reveals disease-tissue associations.
Kang HP, Morgan AA, Chen R, Schadt EE, Butte AJ. Kang HP, et al. Among authors: schadt ee. AMIA Jt Summits Transl Sci Proc. 2012;2012:35-41. Epub 2012 Mar 19. AMIA Jt Summits Transl Sci Proc. 2012. PMID: 22779046 Free PMC article.
Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.
Shang MM, Talukdar HA, Hofmann JJ, Niaudet C, Asl HF, Jain RK, Rossignoli A, Cedergren C, Silveira A, Gigante B, Leander K, de Faire U, Hamsten A, Ruusalepp A, Melander O, Ivert T, Michoel T, Schadt EE, Betsholtz C, Skogsberg J, Björkegren JL. Shang MM, et al. Among authors: schadt ee. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2068-77. doi: 10.1161/ATVBAHA.113.302709. Epub 2014 Jun 12. Arterioscler Thromb Vasc Biol. 2014. PMID: 24925974
Expression quantitative trait Loci acting across multiple tissues are enriched in inherited risk for coronary artery disease.
Foroughi Asl H, Talukdar HA, Kindt AS, Jain RK, Ermel R, Ruusalepp A, Nguyen KD, Dobrin R, Reilly DF, Schunkert H, Samani NJ, Braenne I, Erdmann J, Melander O, Qi J, Ivert T, Skogsberg J, Schadt EE, Michoel T, Björkegren JL; CARDIoGRAM Consortium. Foroughi Asl H, et al. Among authors: schadt ee. Circ Cardiovasc Genet. 2015 Apr;8(2):305-15. doi: 10.1161/CIRCGENETICS.114.000640. Epub 2015 Jan 11. Circ Cardiovasc Genet. 2015. PMID: 25578447 Clinical Trial.
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci.
Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, Schadt EE, Yang X, Samani NJ, Björkegren JL, Erdmann J, Schunkert H, Lusis AJ; Leducq Consortium CAD Genomics‡. Brænne I, et al. Among authors: schadt ee. Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2207-17. doi: 10.1161/ATVBAHA.115.306108. Epub 2015 Aug 20. Arterioscler Thromb Vasc Biol. 2015. PMID: 26293461 Free PMC article.
419 results