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The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses.
Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte L, Faist A, Schöfbänker M, Hrincius E, Hoffmann H, Hoffmann M, Pöhlmann S, Rescher U, Planz O, Ludwig S. Schreiber A, et al. Among authors: schofbanker m. Cell Mol Life Sci. 2022 Jan 10;79(1):65. doi: 10.1007/s00018-021-04085-1. Cell Mol Life Sci. 2022. PMID: 35013790 Free PMC article.
Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA.
Kleinehr J, Schöfbänker M, Daniel K, Günl F, Mohamed FF, Janowski J, Brunotte L, Boergeling Y, Liebmann M, Behrens M, Gerdemann A, Klotz L, Esselen M, Humpf HU, Ludwig S, Hrincius ER. Kleinehr J, et al. Among authors: schofbanker m. PLoS Pathog. 2023 Jul 13;19(7):e1010986. doi: 10.1371/journal.ppat.1010986. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37440521 Free PMC article.
Importance of ACE2 for SARS-CoV-2 Infection of Kidney Cells.
Kroll MK, Schloer S, Candan P, Korthals N, Wenzel C, Ihle H, Gilhaus K, Liedtke KR, Schöfbänker M, Surmann B, Schröter R, Neugebauer U, Mall G, Oswald S, Ludwig S, Rescher U, Vollenbröker B, Ciarimboli G. Kroll MK, et al. Among authors: schofbanker m. Biomolecules. 2023 Mar 3;13(3):472. doi: 10.3390/biom13030472. Biomolecules. 2023. PMID: 36979408 Free PMC article.