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The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis.
Müller A, Dickmanns A, Resch C, Schäkel K, Hailfinger S, Dobbelstein M, Schulze-Osthoff K, Kramer D. Müller A, et al. Among authors: schakel k. J Clin Invest. 2020 Nov 2;130(11):5765-5781. doi: 10.1172/JCI134217. J Clin Invest. 2020. PMID: 32701505 Free PMC article.
[Juckreiz, Schlafstörungen, depressive Symptome, Fatigue und Einschränkungen der Arbeitsproduktivität bei Patienten mit moderater bis schwerer atopischer Dermatitis: Daten aus dem TREATgermany-Register].
Birkner T, Siegels D, Heinrich L, Haufe E, Abraham S, Heratizadeh A, Harder I, Bell M, Fell I, Worm M, Handrick C, Effendy I, Asmussen A, Kleinheinz A, Homey B, Sticherling M, Hong-Weldemann SH, Augustin M, Weisshaar E, Schäkel K, Schaefer T, Schwarz B, Wiemers F, Brücher JJ, Quist S, Wollenberg A, Biedermann T, Ertner K, von Kiedrowski R, Werfel T, Weidinger S, Schmitt J; und die TREATgermany-Studiengruppe. Birkner T, et al. Among authors: schakel k. J Dtsch Dermatol Ges. 2023 Oct;21(10):1157-1169. doi: 10.1111/ddg.15159_g. J Dtsch Dermatol Ges. 2023. PMID: 37845075 German.
Keratinocyte-derived IκBζ drives psoriasis and associated systemic inflammation.
Lorscheid S, Müller A, Löffler J, Resch C, Bucher P, Kurschus FC, Waisman A, Schäkel K, Hailfinger S, Schulze-Osthoff K, Kramer D. Lorscheid S, et al. Among authors: schakel k. JCI Insight. 2019 Nov 14;4(22):e130835. doi: 10.1172/jci.insight.130835. JCI Insight. 2019. PMID: 31622280 Free PMC article.
Psoriasis Pathogenesis and Treatment.
Rendon A, Schäkel K. Rendon A, et al. Among authors: schakel k. Int J Mol Sci. 2019 Mar 23;20(6):1475. doi: 10.3390/ijms20061475. Int J Mol Sci. 2019. PMID: 30909615 Free PMC article. Review.
[Psoriasis].
Sabat R, Schön MP, Schäkel K. Sabat R, et al. Among authors: schakel k. Hautarzt. 2016 Jun;67(6):420-1. doi: 10.1007/s00105-016-3809-z. Hautarzt. 2016. PMID: 27215755 German. No abstract available.
[Pathogenesis of psoriasis].
Schäkel K, Schön MP, Ghoreschi K. Schäkel K, et al. Hautarzt. 2016 Jun;67(6):422-31. doi: 10.1007/s00105-016-3800-8. Hautarzt. 2016. PMID: 27246016 Review. German.
Regulation of IL-22BP in psoriasis.
Voglis S, Moos S, Kloos L, Wanke F, Zayoud M, Pelczar P, Giannou AD, Pezer S, Albers M, Luessi F, Huber S, Schäkel K, Kurschus FC. Voglis S, et al. Among authors: schakel k. Sci Rep. 2018 Mar 23;8(1):5085. doi: 10.1038/s41598-018-23510-3. Sci Rep. 2018. PMID: 29572462 Free PMC article.
Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin.
Orlik C, Deibel D, Küblbeck J, Balta E, Ganskih S, Habicht J, Niesler B, Schröder-Braunstein J, Schäkel K, Wabnitz G, Samstag Y. Orlik C, et al. Among authors: schakel k. Cell Mol Immunol. 2020 Apr;17(4):380-394. doi: 10.1038/s41423-019-0261-x. Epub 2019 Jul 19. Cell Mol Immunol. 2020. PMID: 31324882 Free PMC article.
173 results