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Mutasynthetic Production and Antimicrobial Characterization of Darobactin Analogs.
Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. Böhringer N, et al. Among authors: schaberle tf. Microbiol Spectr. 2021 Dec 22;9(3):e0153521. doi: 10.1128/spectrum.01535-21. Epub 2021 Dec 22. Microbiol Spectr. 2021. PMID: 34937193 Free PMC article.
A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K. Ling LL, et al. Among authors: schaberle tf. Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7. Nature. 2015. PMID: 25561178 Free PMC article.
Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids.
Linares-Otoya L, Liu Y, Linares-Otoya V, Armas-Mantilla L, Crüsemann M, Ganoza-Yupanqui ML, Campos-Florian J, König GM, Schäberle TF. Linares-Otoya L, et al. Among authors: schaberle tf. ACS Chem Biol. 2019 Feb 15;14(2):176-181. doi: 10.1021/acschembio.8b00993. Epub 2019 Jan 18. ACS Chem Biol. 2019. PMID: 30649848
A new antibiotic selectively kills Gram-negative pathogens.
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: schaberle tf. Nature. 2019 Dec;576(7787):459-464. doi: 10.1038/s41586-019-1791-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31747680 Free PMC article.
94 results