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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, Pinschewer DD. Marx AF, et al. Among authors: scarpellino l. Immunity. 2023 Apr 11;56(4):813-828.e10. doi: 10.1016/j.immuni.2023.01.029. Epub 2023 Feb 20. Immunity. 2023. PMID: 36809763 Free article.
TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.
Ronet C, Passelli K, Charmoy M, Scarpellino L, Myburgh E, Hauyon La Torre Y, Turco S, Mottram JC, Fasel N, Luther SA, Beverley SM, Launois P, Tacchini-Cottier F. Ronet C, et al. Among authors: scarpellino l. J Invest Dermatol. 2019 Jun;139(6):1318-1328. doi: 10.1016/j.jid.2018.12.012. Epub 2018 Dec 27. J Invest Dermatol. 2019. PMID: 30594488 Free PMC article.
Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.
Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA. Schaeuble K, et al. Among authors: scarpellino l. Cell Rep. 2017 Nov 28;21(9):2500-2514. doi: 10.1016/j.celrep.2017.10.119. Cell Rep. 2017. PMID: 29186687 Free article.
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Corria-Osorio J, Carmona SJ, Stefanidis E, Andreatta M, Ortiz-Miranda Y, Muller T, Rota IA, Crespo I, Seijo B, Castro W, Jimenez-Luna C, Scarpellino L, Ronet C, Spill A, Lanitis E, Romero P, Luther SA, Irving M, Coukos G. Corria-Osorio J, et al. Among authors: scarpellino l. Nat Immunol. 2023 May;24(5):869-883. doi: 10.1038/s41590-023-01477-2. Epub 2023 Apr 20. Nat Immunol. 2023. PMID: 37081150 Free PMC article.
In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B, Reverte M, Ronet C, Prevel F, Morgenthaler FD, Desponds C, Lye LF, Owens KL, Scarpellino L, Dubey LK, Sabine A, Petrova TV, Luther SA, Beverley SM, Fasel N. Jha B, et al. Among authors: scarpellino l. Front Cell Infect Microbiol. 2022 Aug 12;12:941860. doi: 10.3389/fcimb.2022.941860. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36034709 Free PMC article.
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.
Pais Ferreira D, Silva JG, Wyss T, Fuertes Marraco SA, Scarpellino L, Charmoy M, Maas R, Siddiqui I, Tang L, Joyce JA, Delorenzi M, Luther SA, Speiser DE, Held W. Pais Ferreira D, et al. Among authors: scarpellino l. Immunity. 2020 Nov 17;53(5):985-1000.e11. doi: 10.1016/j.immuni.2020.09.005. Epub 2020 Oct 30. Immunity. 2020. PMID: 33128876 Free article.
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I, Schaeuble K, Chennupati V, Fuertes Marraco SA, Calderon-Copete S, Pais Ferreira D, Carmona SJ, Scarpellino L, Gfeller D, Pradervand S, Luther SA, Speiser DE, Held W. Siddiqui I, et al. Among authors: scarpellino l. Immunity. 2019 Jan 15;50(1):195-211.e10. doi: 10.1016/j.immuni.2018.12.021. Epub 2019 Jan 8. Immunity. 2019. PMID: 30635237 Free article.
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.
Huang HY, Rivas-Caicedo A, Renevey F, Cannelle H, Peranzoni E, Scarpellino L, Hardie DL, Pommier A, Schaeuble K, Favre S, Vogt TK, Arenzana-Seisdedos F, Schneider P, Buckley CD, Donnadieu E, Luther SA. Huang HY, et al. Among authors: scarpellino l. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6826-E6835. doi: 10.1073/pnas.1712628115. Epub 2018 Jul 2. Proc Natl Acad Sci U S A. 2018. PMID: 29967180 Free PMC article.
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Chung J, et al. Among authors: scarpellino l. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319044 Free PMC article.
51 results