Scanlan EM - Search Results

1

Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis.

Olatunji S, Bowen K, Huang CY, Weichert D, Singh W, Tikhonova IG, Scanlan EM, Olieric V, Caffrey M. Olatunji S, et al. Among authors: scanlan em. Nat Commun. 2021 Jul 12;12(1):4254. doi: 10.1038/s41467-021-24475-0. Nat Commun. 2021. PMID: 34253723 Free PMC article.

2

Exploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology.

Burke HM, McSweeney L, Scanlan EM. Burke HM, et al. Among authors: scanlan em. Nat Commun. 2017 May 24;8:15655. doi: 10.1038/ncomms15655. Nat Commun. 2017. PMID: 28537277 Free PMC article. Review.

3

Chemoselective Synthesis of N-Terminal Cysteinyl Thioesters via β,γ-C,S Thiol-Michael Addition.

Petracca R, Bowen KA, McSweeney L, O'Flaherty S, Genna V, Twamley B, Devocelle M, Scanlan EM. Petracca R, et al. Among authors: scanlan em. Org Lett. 2019 May 3;21(9):3281-3285. doi: 10.1021/acs.orglett.9b01013. Epub 2019 Apr 24. Org Lett. 2019. PMID: 31017793

4

Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.

Olatunji S, Yu X, Bailey J, Huang CY, Zapotoczna M, Bowen K, Remškar M, Müller R, Scanlan EM, Geoghegan JA, Olieric V, Caffrey M. Olatunji S, et al. Among authors: scanlan em. Nat Commun. 2020 Jan 9;11(1):140. doi: 10.1038/s41467-019-13724-y. Nat Commun. 2020. PMID: 31919415 Free PMC article.

5

Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N-acyltransferase.

Smithers L, Degtjarik O, Weichert D, Huang CY, Boland C, Bowen K, Oluwole A, Lutomski C, Robinson CV, Scanlan EM, Wang M, Olieric V, Shalev-Benami M, Caffrey M. Smithers L, et al. Among authors: scanlan em. Sci Adv. 2023 Jun 30;9(26):eadf5799. doi: 10.1126/sciadv.adf5799. Epub 2023 Jun 30. Sci Adv. 2023. PMID: 37390210 Free PMC article.

6

Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase.

Craven TW, Nolan MD, Bailey J, Olatunji S, Bann SJ, Bowen K, Ostrovitsa N, Da Costa TM, Ballantine RD, Weichert D, Levine PM, Stewart LJ, Bhardwaj G, Geoghegan JA, Cochrane SA, Scanlan EM, Caffrey M, Baker D. Craven TW, et al. Among authors: scanlan em. ACS Chem Biol. 2024 May 7. doi: 10.1021/acschembio.4c00076. Online ahead of print. ACS Chem Biol. 2024. PMID: 38712757

7

Intramolecular thiol-yne cyclisation as a novel strategy for thioglycal synthesis.

Corcé V, McSweeney L, Malone A, Scanlan EM. Corcé V, et al. Among authors: scanlan em. Chem Commun (Camb). 2015 May 21;51(41):8672-4. doi: 10.1039/c5cc02162f. Chem Commun (Camb). 2015. PMID: 25907977

8

Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated 'pro-probes'.

Calatrava-Pérez E, Bright SA, Achermann S, Moylan C, Senge MO, Veale EB, Williams DC, Gunnlaugsson T, Scanlan EM. Calatrava-Pérez E, et al. Among authors: scanlan em. Chem Commun (Camb). 2016 Nov 18;52(89):13086-13089. doi: 10.1039/c6cc06451e. Epub 2016 Sep 27. Chem Commun (Camb). 2016. PMID: 27722254

9

Recent advances in the development of synthetic chemical probes for glycosidase enzymes.

Burke HM, Gunnlaugsson T, Scanlan EM. Burke HM, et al. Among authors: scanlan em. Chem Commun (Camb). 2015 Jul 7;51(53):10576-88. doi: 10.1039/c5cc02793d. Epub 2015 Jun 8. Chem Commun (Camb). 2015. PMID: 26051717 Review.

10

The synthesis and biological evaluation of mycobacterial p-hydroxybenzoic acid derivatives (p-HBADs).

Bourke J, Brereton CF, Gordon SV, Lavelle EC, Scanlan EM. Bourke J, et al. Among authors: scanlan em. Org Biomol Chem. 2014 Feb 21;12(7):1114-23. doi: 10.1039/c3ob42277a. Org Biomol Chem. 2014. PMID: 24424275

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