Savinov AY - Search Results

1

Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.

Radichev IA, Maneva-Radicheva LV, Amatya C, Salehi M, Parker C, Ellefson J, Burn P, Savinov AY. Radichev IA, et al. Among authors: savinov ay. J Immunol. 2016 Feb 15;196(4):1495-506. doi: 10.4049/jimmunol.1403251. Epub 2016 Jan 15. J Immunol. 2016. PMID: 26773144 Free PMC article.

2

The Type 1 Diabetes-Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice.

Whitener RL, Gallo Knight L, Li J, Knapp S, Zhang S, Annamalai M, Pliner VM, Fu D, Radichev I, Amatya C, Savinov A, Yurdagul A Jr, Yuan S, Glawe J, Kevil CG, Chen J, Stimpson SE, Mathews CE. Whitener RL, et al. J Immunol. 2017 Dec 15;199(12):3991-4000. doi: 10.4049/jimmunol.1602037. Epub 2017 Nov 6. J Immunol. 2017. PMID: 29109122 Free PMC article.

3

Self-Transducible Bimodal PDX1-FOXP3 Protein Lifts Insulin Secretion and Curbs Autoimmunity, Boosting Tregs in Type 1 Diabetic Mice.

Amatya C, Radichev IA, Ellefson J, Williams M, Savinov AY. Amatya C, et al. Among authors: savinov ay. Mol Ther. 2018 Jan 3;26(1):184-198. doi: 10.1016/j.ymthe.2017.08.014. Epub 2017 Sep 7. Mol Ther. 2018. PMID: 28988715 Free PMC article.

4

Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor.

Radichev IA, Yoon J, Scott DW, Griffin K, Savinov AY. Radichev IA, et al. Among authors: savinov ay. Cell Immunol. 2020 Dec;358:104224. doi: 10.1016/j.cellimm.2020.104224. Epub 2020 Sep 30. Cell Immunol. 2020. PMID: 33068914 Free PMC article.

5

Interference with islet-specific homing of autoreactive T cells: an emerging therapeutic strategy for type 1 diabetes.

Savinov AY, Burn P. Savinov AY, et al. Drug Discov Today. 2010 Jul;15(13-14):531-9. doi: 10.1016/j.drudis.2010.05.013. Drug Discov Today. 2010. PMID: 20685342 Review.

6

Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.

Radichev IA, Maneva-Radicheva LV, Amatya C, Parker C, Ellefson J, Wasserfall C, Atkinson M, Burn P, Savinov AY. Radichev IA, et al. Among authors: savinov ay. Diabetes. 2014 Oct;63(10):3470-82. doi: 10.2337/db14-0213. Epub 2014 May 21. Diabetes. 2014. PMID: 24848066 Free PMC article.

7

Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1.

Maneva-Radicheva L, Amatya C, Parker C, Ellefson J, Radichev I, Raghavan A, Charles ML, Williams MS, Robbins MS, Savinov AY. Maneva-Radicheva L, et al. Among authors: savinov ay. PLoS One. 2014 Sep 26;9(9):e107213. doi: 10.1371/journal.pone.0107213. eCollection 2014. PLoS One. 2014. PMID: 25259810 Free PMC article.

8

Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus.

Kolodka T, Charles ML, Raghavan A, Radichev IA, Amatya C, Ellefson J, Savinov AY, Nag A, Williams MS, Robbins MS. Kolodka T, et al. Among authors: savinov ay. PLoS One. 2014 Aug 6;9(8):e103981. doi: 10.1371/journal.pone.0103981. eCollection 2014. PLoS One. 2014. PMID: 25100328 Free PMC article.

9

Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes.

Armitage LH, Stimpson SE, Santostefano KE, Sui L, Ogundare S, Newby BN, Castro-Gutierrez R, Huber MK, Taylor JP, Sharma P, Radichev IA, Perry DJ, Fredette NC, Savinov AY, Wallet MA, Terada N, Brusko TM, Russ HA, Chen J, Egli D, Mathews CE. Armitage LH, et al. Among authors: savinov ay. Front Endocrinol (Lausanne). 2021 Nov 9;12:737276. doi: 10.3389/fendo.2021.737276. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34858326 Free PMC article.

10

Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification.

Savinov AY, Salehi M, Yadav MC, Radichev I, Millán JL, Savinova OV. Savinov AY, et al. J Am Heart Assoc. 2015 Dec 16;4(12):e002499. doi: 10.1161/JAHA.115.002499. J Am Heart Assoc. 2015. PMID: 26675253 Free PMC article.

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