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Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.
Bonadona V, Bonaïti B, Olschwang S, Grandjouan S, Huiart L, Longy M, Guimbaud R, Buecher B, Bignon YJ, Caron O, Colas C, Noguès C, Lejeune-Dumoulin S, Olivier-Faivre L, Polycarpe-Osaer F, Nguyen TD, Desseigne F, Saurin JC, Berthet P, Leroux D, Duffour J, Manouvrier S, Frébourg T, Sobol H, Lasset C, Bonaïti-Pellié C; French Cancer Genetics Network. Bonadona V, et al. Among authors: saurin jc. JAMA. 2011 Jun 8;305(22):2304-10. doi: 10.1001/jama.2011.743. JAMA. 2011. PMID: 21642682
Germline hMSH2 and hMLH1 gene mutations in incomplete HNPCC families.
Wang Q, Desseigne F, Lasset C, Saurin JC, Navarro C, Yagci T, Keser I, Bagci H, Luleci G, Gelen T, Chayvialle JA, Puisieux A, Ozturk M. Wang Q, et al. Among authors: saurin jc. Int J Cancer. 1997 Dec 10;73(6):831-6. doi: 10.1002/(sici)1097-0215(19971210)73:6<831::aid-ijc11>3.0.co;2-7. Int J Cancer. 1997. PMID: 9399661 Free article.
Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles.
Auclair J, Vaissière T, Desseigne F, Lasset C, Bonadona V, Giraud S, Saurin JC, Joly MO, Leroux D, Faivre L, Audoynaud C, Montmain G, Ruano E, Herceg Z, Puisieux A, Wang Q. Auclair J, et al. Among authors: saurin jc. Genes Chromosomes Cancer. 2011 Mar;50(3):178-85. doi: 10.1002/gcc.20842. Epub 2010 Dec 9. Genes Chromosomes Cancer. 2011. PMID: 21213371
Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.
Coissieux MM, Tomsic J, Castets M, Hampel H, Tuupanen S, Andrieu N, Comeras I, Drouet Y, Lasset C, Liyanarachchi S, Mazelin L, Puisieux A, Saurin JC, Scoazec JY, Wang Q, Aaltonen L, Tanner SM, de la Chapelle A, Bernet A, Mehlen P. Coissieux MM, et al. Among authors: saurin jc. Gastroenterology. 2011 Dec;141(6):2039-46. doi: 10.1053/j.gastro.2011.08.041. Epub 2011 Sep 3. Gastroenterology. 2011. PMID: 21893118 Free PMC article.
239 results