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Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors.
Molecules. 2021 Sep 2;26(17):5349. doi: 10.3390/molecules26175349.
Molecules. 2021.
PMID: 34500781
Free PMC article.
Design, synthesis, and biological activity of pyridopyrimidine scaffolds as novel PI3K/mTOR dual inhibitors.
Saurat T, Buron F, Rodrigues N, de Tauzia ML, Colliandre L, Bourg S, Bonnet P, Guillaumet G, Akssira M, Corlu A, Guillouzo C, Berthier P, Rio P, Jourdan ML, Bénédetti H, Routier S.
Saurat T, et al.
J Med Chem. 2014 Feb 13;57(3):613-31. doi: 10.1021/jm401138v. Epub 2014 Jan 21.
J Med Chem. 2014.
PMID: 24345273
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New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway.
Nehmé R, Nehmé H, Saurat T, de-Tauzia ML, Buron F, Lafite P, Verrelle P, Chautard E, Morin P, Routier S, Bénédetti H.
Nehmé R, et al. Among authors: saurat t.
Anal Bioanal Chem. 2014 Jun;406(15):3743-54. doi: 10.1007/s00216-014-7790-z. Epub 2014 May 11.
Anal Bioanal Chem. 2014.
PMID: 24817345
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