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Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis.
Maddali MV, Churpek M, Pham T, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P; LUNG SAFE Investigators and the ESICM Trials Group. Maddali MV, et al. Among authors: sarma a. Lancet Respir Med. 2022 Apr;10(4):367-377. doi: 10.1016/S2213-2600(21)00461-6. Epub 2022 Jan 10. Lancet Respir Med. 2022. PMID: 35026177 Free PMC article.
Biomarkers and Precision Medicine: State of the Art.
Sarma A, Calfee CS, Ware LB. Sarma A, et al. Crit Care Clin. 2020 Jan;36(1):155-165. doi: 10.1016/j.ccc.2019.08.012. Epub 2019 Oct 22. Crit Care Clin. 2020. PMID: 31733677 Review.
Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19.
Tsitsiklis A, Zha BS, Byrne A, Devoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Jones N, Wu B, Darmanis S, Matthay MA, Lynch SV, DeRisi JL; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. Tsitsiklis A, et al. Among authors: sarma a. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-380803. doi: 10.21203/rs.3.rs-380803/v1. Res Sq. 2021. PMID: 34013247 Free PMC article. Preprint.
Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study.
Sinha P, Delucchi KL, Chen Y, Zhuo H, Abbott J, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Calfee CS. Sinha P, et al. Among authors: sarma a. Thorax. 2022 Jan;77(1):13-21. doi: 10.1136/thoraxjnl-2021-217158. Epub 2021 Jul 12. Thorax. 2022. PMID: 34253679 Free PMC article.
Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS.
Sarma A, Christenson SA, Byrne A, Mick E, Pisco AO, DeVoe C, Deiss T, Ghale R, Zha BS, Tsitsiklis A, Jauregui A, Moazed F, Detweiler AM, Spottiswoode N, Sinha P, Neff N, Tan M, Serpa PH, Willmore A, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR. Sarma A, et al. Nat Commun. 2021 Aug 26;12(1):5152. doi: 10.1038/s41467-021-25040-5. Nat Commun. 2021. PMID: 34446707 Free PMC article.
Impact of e-cigarette aerosol on primary human alveolar epithelial type 2 cells.
Wick KD, Fang X, Maishan M, Matsumoto S, Spottiswoode N, Sarma A, Simoneau C, Khakoo M, Langelier C, Calfee CS, Gotts JE, Matthay MA. Wick KD, et al. Among authors: sarma a. Am J Physiol Lung Cell Mol Physiol. 2022 Aug 1;323(2):L152-L164. doi: 10.1152/ajplung.00503.2021. Epub 2022 Jun 7. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35670478 Free PMC article.
Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults.
Kalantar KL, Neyton L, Abdelghany M, Mick E, Jauregui A, Caldera S, Serpa PH, Ghale R, Albright J, Sarma A, Tsitsiklis A, Leligdowicz A, Christenson SA, Liu K, Kangelaris KN, Hendrickson C, Sinha P, Gomez A, Neff N, Pisco A, Doernberg SB, Derisi JL, Matthay MA, Calfee CS, Langelier CR. Kalantar KL, et al. Among authors: sarma a. Nat Microbiol. 2022 Nov;7(11):1805-1816. doi: 10.1038/s41564-022-01237-2. Epub 2022 Oct 20. Nat Microbiol. 2022. PMID: 36266337 Free PMC article. Clinical Trial.
Aerosolized nicotine from e-cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection.
Maishan M, Sarma A, Chun LF, Caldera S, Fang X, Abbott J, Christenson SA, Langelier CR, Calfee CS, Gotts JE, Matthay MA. Maishan M, et al. Among authors: sarma a. Front Immunol. 2023 Mar 14;14:1076772. doi: 10.3389/fimmu.2023.1076772. eCollection 2023. Front Immunol. 2023. PMID: 36999019 Free PMC article.
Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19.
Neyton LPA, Patel RK, Sarma A; UCSF COMET Consortium; Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. Neyton LPA, et al. Among authors: sarma a. Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3168149. doi: 10.21203/rs.3.rs-3168149/v1. Res Sq. 2023. PMID: 37577607 Free PMC article. Preprint.
523 results