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Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy.
Migliozzi S, Oh YT, Hasanain M, Garofano L, D'Angelo F, Najac RD, Picca A, Bielle F, Di Stefano AL, Lerond J, Sarkaria JN, Ceccarelli M, Sanson M, Lasorella A, Iavarone A. Migliozzi S, et al. Among authors: sarkaria jn. Nat Cancer. 2023 Feb;4(2):181-202. doi: 10.1038/s43018-022-00510-x. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732634 Free PMC article.
Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy.
Kurokawa C, Iankov ID, Anderson SK, Aderca I, Leontovich AA, Maurer MJ, Oberg AL, Schroeder MA, Giannini C, Greiner SM, Becker MA, Thompson EA, Haluska P, Jentoft ME, Parney IF, Weroha SJ, Jen J, Sarkaria JN, Galanis E. Kurokawa C, et al. Among authors: sarkaria jn. J Natl Cancer Inst. 2018 Oct 1;110(10):1123-1132. doi: 10.1093/jnci/djy033. J Natl Cancer Inst. 2018. PMID: 29788332 Free PMC article. Clinical Trial.
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.
Zhou W, Yao Y, Scott AJ, Wilder-Romans K, Dresser JJ, Werner CK, Sun H, Pratt D, Sajjakulnukit P, Zhao SG, Davis M, Nelson BS, Halbrook CJ, Zhang L, Gatto F, Umemura Y, Walker AK, Kachman M, Sarkaria JN, Xiong J, Morgan MA, Rehemtualla A, Castro MG, Lowenstein P, Chandrasekaran S, Lawrence TS, Lyssiotis CA, Wahl DR. Zhou W, et al. Among authors: sarkaria jn. Nat Commun. 2020 Jul 30;11(1):3811. doi: 10.1038/s41467-020-17512-x. Nat Commun. 2020. PMID: 32732914 Free PMC article.
258 results