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Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes.
Petrigliano FA, Liu NQ, Lee S, Tassey J, Sarkar A, Lin Y, Li L, Yu Y, Geng D, Zhang J, Shkhyan R, Bogdanov J, Van Handel B, Ferguson GB, Lee Y, Hinderer S, Tseng KC, Kavanaugh A, Crump JG, Pyle AD, Schenke-Layland K, Billi F, Wang L, Lieberman J, Hurtig M, Evseenko D. Petrigliano FA, et al. Among authors: sarkar a. NPJ Regen Med. 2021 Nov 23;6(1):77. doi: 10.1038/s41536-021-00187-3. NPJ Regen Med. 2021. PMID: 34815400 Free PMC article.
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Harn HI, Wang SP, Lai YC, Van Handel B, Liang YC, Tsai S, Schiessl IM, Sarkar A, Xi H, Hughes M, Kaemmer S, Tang MJ, Peti-Peterdi J, Pyle AD, Woolley TE, Evseenko D, Jiang TX, Chuong CM. Harn HI, et al. Among authors: sarkar a. Nat Commun. 2021 May 10;12(1):2595. doi: 10.1038/s41467-021-22822-9. Nat Commun. 2021. PMID: 33972536 Free PMC article.
gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes.
Liu NQ, Lin Y, Li L, Lu J, Geng D, Zhang J, Jashashvili T, Buser Z, Magallanes J, Tassey J, Shkhyan R, Sarkar A, Lopez N, Lee S, Lee Y, Wang L, Petrigliano FA, Van Handel B, Lyons K, Evseenko D. Liu NQ, et al. Among authors: sarkar a. Commun Biol. 2022 Jan 17;5(1):64. doi: 10.1038/s42003-021-02944-y. Commun Biol. 2022. PMID: 35039652 Free PMC article.
Author Correction: gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes.
Liu NQ, Lin Y, Li L, Lu J, Geng D, Zhang J, Jashashvili T, Buser Z, Magallanes J, Tassey J, Shkhyan R, Sarkar A, Lopez N, Lee S, Lee Y, Wang L, Petrigliano FA, Van Handel B, Lyons K, Evseenko D. Liu NQ, et al. Among authors: sarkar a. Commun Biol. 2022 Feb 25;5(1):200. doi: 10.1038/s42003-022-03167-5. Commun Biol. 2022. PMID: 35217719 Free PMC article. No abstract available.
STAT3 promotes a youthful epigenetic state in articular chondrocytes.
Sarkar A, Liu NQ, Magallanes J, Tassey J, Lee S, Shkhyan R, Lee Y, Lu J, Ouyang Y, Tang H, Bian F, Tao L, Segil N, Ernst J, Lyons K, Horvath S, Evseenko D. Sarkar A, et al. Aging Cell. 2023 Feb;22(2):e13773. doi: 10.1111/acel.13773. Epub 2023 Jan 13. Aging Cell. 2023. PMID: 36638270 Free PMC article.
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis.
Shkhyan R, Flynn C, Lamoure E, Sarkar A, Van Handel B, Li J, York J, Banks N, Van der Horst R, Liu NQ, Lee S, Bajaj P, Vadivel K, Harn HI, Tassey J, Lozito T, Lieberman JR, Chuong CM, Hurtig MS, Evseenko D. Shkhyan R, et al. Among authors: sarkar a. Sci Transl Med. 2023 Mar 22;15(688):eabq2395. doi: 10.1126/scitranslmed.abq2395. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947594 Free PMC article.
Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet.
Lee Y, Sarkar A, Tassey J, Levi JN, Lee S, Liu NQ, Drake AC, Magallanes J, Stevic U, Lu J, Ge D, Tang H, Mkaratigwa T, Bian F, Shkhyan R, Bonaguidi M, Evseenko D. Lee Y, et al. Among authors: sarkar a. bioRxiv [Preprint]. 2024 Apr 11:2024.04.08.588362. doi: 10.1101/2024.04.08.588362. bioRxiv. 2024. PMID: 38645030 Free PMC article. Preprint.
2,452 results