Sarafianos SG - Search Results

1

Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus.

Martinez-Lopez A, Persaud M, Chavez MP, Zhang H, Rong L, Liu S, Wang TT, Sarafianos SG, Diaz-Griffero F. Martinez-Lopez A, et al. Among authors: sarafianos sg. EBioMedicine. 2019 Sep;47:269-283. doi: 10.1016/j.ebiom.2019.08.060. Epub 2019 Sep 6. EBioMedicine. 2019. PMID: 31501074 Free PMC article.

2

TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.

Selyutina A, Simons LM, Kirby KA, Bulnes-Ramos A, Hu P, Sarafianos SG, Hultquist JF, Diaz-Griffero F. Selyutina A, et al. Among authors: sarafianos sg. Viruses. 2022 Feb 10;14(2):363. doi: 10.3390/v14020363. Viruses. 2022. PMID: 35215956 Free PMC article.

3

Chemical profiling of HIV-1 capsid-targeting antiviral PF74.

Wang L, Casey MC, Vernekar SKV, Do HT, Sahani RL, Kirby KA, Du H, Hachiya A, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Wang L, et al. Among authors: sarafianos sg. Eur J Med Chem. 2020 Aug 15;200:112427. doi: 10.1016/j.ejmech.2020.112427. Epub 2020 May 12. Eur J Med Chem. 2020. PMID: 32438252 Free PMC article.

4

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches.

Senaweera S, Du H, Zhang H, Kirby KA, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Senaweera S, et al. Among authors: sarafianos sg. Viruses. 2021 Apr 27;13(5):770. doi: 10.3390/v13050770. Viruses. 2021. PMID: 33925540 Free PMC article.

5

3-Hydroxypyrimidine-2,4-Diones as Novel Hepatitis B Virus Antivirals Targeting the Viral Ribonuclease H.

Huber AD, Michailidis E, Tang J, Puray-Chavez MN, Boftsi M, Wolf JJ, Boschert KN, Sheridan MA, Leslie MD, Kirby KA, Singh K, Mitsuya H, Parniak MA, Wang Z, Sarafianos SG. Huber AD, et al. Among authors: sarafianos sg. Antimicrob Agents Chemother. 2017 May 24;61(6):e00245-17. doi: 10.1128/AAC.00245-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28320718 Free PMC article.

6

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: sarafianos sg. Eur J Med Chem. 2018 Aug 5;156:652-665. doi: 10.1016/j.ejmech.2018.07.039. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031976 Free PMC article.

7

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: sarafianos sg. Eur J Med Chem. 2018 Aug 5;156:680-691. doi: 10.1016/j.ejmech.2018.07.035. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031978 Free PMC article.

8

Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus.

Liu D, Tedbury PR, Lan S, Huber AD, Puray-Chavez MN, Ji J, Michailidis E, Saeed M, Ndongwe TP, Bassit LC, Schinazi RF, Ralston R, Rice CM, Sarafianos SG. Liu D, et al. Among authors: sarafianos sg. Viruses. 2019 Nov 8;11(11):1039. doi: 10.3390/v11111039. Viruses. 2019. PMID: 31717338 Free PMC article.

9

Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules.

Vernekar SKV, Sahani RL, Casey MC, Kankanala J, Wang L, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Vernekar SKV, et al. Among authors: sarafianos sg. Viruses. 2020 Apr 16;12(4):452. doi: 10.3390/v12040452. Viruses. 2020. PMID: 32316297 Free PMC article.

10

Single-cell Multiplexed Fluorescence Imaging to Visualize Viral Nucleic Acids and Proteins and Monitor HIV, HTLV, HBV, HCV, Zika Virus, and Influenza Infection.

Shah R, Lan S, Puray-Chavez MN, Liu D, Tedbury PR, Sarafianos SG. Shah R, et al. Among authors: sarafianos sg. J Vis Exp. 2020 Oct 29;(164):10.3791/61843. doi: 10.3791/61843. J Vis Exp. 2020. PMID: 33191939 Free PMC article.

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