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Page 1
Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from Leishmania mexicana with Biological Activity against Promastigotes and Amastigotes.
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A. Betancourt-Conde I, et al. Among authors: mendez st. Int J Mol Sci. 2021 Dec 19;22(24):13613. doi: 10.3390/ijms222413613. Int J Mol Sci. 2021. PMID: 34948408 Free PMC article.
Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors.
Campos-Almazán MI, Flores-Ramos M, Hernández-Campos A, Castillo R, Sierra-Campos E, Torgeson K, Peti W, Valdez-Solana M, Oria-Hernández J, Méndez ST, Castillo-Villanueva A, Jiménez-de Jesús H, Avitia-Domínguez C, Téllez-Valencia A. Campos-Almazán MI, et al. Among authors: mendez st. Bioorg Med Chem. 2021 Oct 15;48:116418. doi: 10.1016/j.bmc.2021.116418. Epub 2021 Sep 17. Bioorg Med Chem. 2021. PMID: 34563877
Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis.
Navarrete-Vázquez G, Chávez-Silva F, Colín-Lozano B, Estrada-Soto S, Hidalgo-Figueroa S, Guerrero-Álvarez J, Méndez ST, Reyes-Vivas H, Oria-Hernández J, Canul-Canché J, Ortiz-Andrade R, Moo-Puc R. Navarrete-Vázquez G, et al. Among authors: mendez st. Bioorg Med Chem. 2015 May 1;23(9):2204-10. doi: 10.1016/j.bmc.2015.02.059. Epub 2015 Mar 10. Bioorg Med Chem. 2015. PMID: 25801157
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Reyes-Vivas H, de la Mora-de la Mora I, Castillo-Villanueva A, Yépez-Mulia L, Hernández-Alcántara G, Figueroa-Salazar R, García-Torres I, Gómez-Manzo S, Méndez ST, Vanoye-Carlo A, Marcial-Quino J, Torres-Arroyo A, Oria-Hernández J, Gutiérrez-Castrellón P, Enríquez-Flores S, López-Velázquez G. Reyes-Vivas H, et al. Among authors: mendez st. Antimicrob Agents Chemother. 2014 Dec;58(12):7072-82. doi: 10.1128/AAC.02900-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223993 Free PMC article.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
De La Mora-De La Mora I, Torres-Larios A, Mendoza-Hernández G, Enriquez-Flores S, Castillo-Villanueva A, Mendez ST, Garcia-Torres I, Torres-Arroyo A, Gómez-Manzo S, Marcial-Quino J, Oria-Hernández J, López-Velázquez G, Reyes-Vivas H. De La Mora-De La Mora I, et al. Among authors: mendez st. Biochim Biophys Acta. 2013 Dec;1834(12):2702-11. doi: 10.1016/j.bbapap.2013.08.012. Epub 2013 Sep 20. Biochim Biophys Acta. 2013. PMID: 24056040
Structural and functional perturbation of Giardia lamblia triosephosphate isomerase by modification of a non-catalytic, non-conserved region.
Hernández-Alcántara G, Torres-Larios A, Enríquez-Flores S, García-Torres I, Castillo-Villanueva A, Méndez ST, de la Mora-de la Mora I, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H, Oria-Hernández J. Hernández-Alcántara G, et al. Among authors: mendez st. PLoS One. 2013 Jul 22;8(7):e69031. doi: 10.1371/journal.pone.0069031. Print 2013. PLoS One. 2013. PMID: 23894402 Free PMC article.
Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: a study for antiparasitic drug design.
Enríquez-Flores S, Rodríguez-Romero A, Hernández-Alcántara G, Oria-Hernández J, Gutiérrez-Castrellón P, Pérez-Hernández G, de la Mora-de la Mora I, Castillo-Villanueva A, García-Torres I, Méndez ST, Gómez-Manzo S, Torres-Arroyo A, López-Velázquez G, Reyes-Vivas H. Enríquez-Flores S, et al. Among authors: mendez st. Proteins. 2011 Sep;79(9):2711-24. doi: 10.1002/prot.23100. Epub 2011 Jul 22. Proteins. 2011. PMID: 21786322
Avian influenza: genetic evolution under vaccination pressure.
Escorcia M, Vázquez L, Méndez ST, Rodríguez-Ropón A, Lucio E, Nava GM. Escorcia M, et al. Among authors: mendez st. Virol J. 2008 Jan 24;5:15. doi: 10.1186/1743-422X-5-15. Virol J. 2008. PMID: 18218105 Free PMC article.