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2015 2
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Investigating the promising SARS-CoV-2 main protease inhibitory activity of secoiridoids isolated from Jasminum humile; in silico and in Vitro assessments with structure-activity relationship.
Al-Karmalawy AA, Alnajjar R, Elmaaty AA, Binjubair FA, Al-Rashood ST, Mansour BS, Elkamhawy A, Eldehna WM, Mansour KA. Al-Karmalawy AA, et al. J Biomol Struct Dyn. 2023 Jul 28:1-13. doi: 10.1080/07391102.2023.2240419. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 37505066
Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human colorectal cancer.
Eldehna WM, Mohammed EE, Al-Ansary GH, Berrino E, Elbadawi MM, Ibrahim TM, Jaballah MY, Al-Rashood ST, Binjubair FA, Celik M, Nocentini A, Elbarbry FA, Sahin F, Abdel-Aziz HA, Supuran CT, Fares M. Eldehna WM, et al. Eur J Med Chem. 2023 Oct 5;258:115538. doi: 10.1016/j.ejmech.2023.115538. Epub 2023 Jun 1. Eur J Med Chem. 2023. PMID: 37321108
Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies.
Al-Karmalawy AA, El-Gamil DS, El-Shesheny R, Sharaky M, Alnajjar R, Kutkat O, Moatasim Y, Elagawany M, Al-Rashood ST, Binjubair FA, Eldehna WM, Noreddin AM, Zakaria MY. Al-Karmalawy AA, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2202357. doi: 10.1080/14756366.2023.2202357. J Enzyme Inhib Med Chem. 2023. PMID: 37092260 Free PMC article.
Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.
Badawi WA, Rashed M, Nocentini A, Bonardi A, Abd-Alhaseeb MM, Al-Rashood ST, Veerakanellore GB, Majrashi TA, Elkaeed EB, Elgendy B, Gratteri P, Supuran CT, Eldehna WM, Elagawany M. Badawi WA, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2201407. doi: 10.1080/14756366.2023.2201407. J Enzyme Inhib Med Chem. 2023. PMID: 37078173 Free PMC article.
63 results