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Synthesis and biological evaluation of new penta- and heptacyclic indolo- and quinolinocarbazole ring systems obtained via Pd(0) catalysed reductive N-heteroannulation.
Laronze-Cochard M, Cochard F, Daras E, Lansiaux A, Brassart B, Vanquelef E, Prost E, Nuzillard JM, Baldeyrou B, Goosens JF, Lozach O, Meijer L, Riou JF, Henon E, Sapi J. Laronze-Cochard M, et al. Among authors: sapi j. Org Biomol Chem. 2010 Oct 21;8(20):4625-36. doi: 10.1039/c0ob00149j. Epub 2010 Aug 24. Org Biomol Chem. 2010. PMID: 20734015
Cytotoxic bis-3,4-dihydro-beta-carbolines and bis-beta-carbolines.
Jiang WQ, Charlet-Fagnère C, Sapi J, Laronze JY, Renard P, Pfeiffer B, Léonce S. Jiang WQ, et al. Among authors: sapi j. J Enzyme Inhib Med Chem. 2002 Dec;17(6):369-74. doi: 10.1080/147563021000005631. J Enzyme Inhib Med Chem. 2002. PMID: 12683671
Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.
Ledour G, Moroy G, Rouffet M, Bourguet E, Guillaume D, Decarme M, Elmourabit H, Augé F, Alix AJ, Laronze JY, Bellon G, Hornebeck W, Sapi J. Ledour G, et al. Among authors: sapi j. Bioorg Med Chem. 2008 Sep 15;16(18):8745-59. doi: 10.1016/j.bmc.2008.07.041. Epub 2008 Jul 20. Bioorg Med Chem. 2008. PMID: 18782669
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.
Cornelio B, Laronze-Cochard M, Ceruso M, Ferraroni M, Rance GA, Carta F, Khlobystov AN, Fontana A, Supuran CT, Sapi J. Cornelio B, et al. Among authors: sapi j. J Med Chem. 2016 Jan 28;59(2):721-32. doi: 10.1021/acs.jmedchem.5b01771. Epub 2016 Jan 15. J Med Chem. 2016. PMID: 26741028
43 results