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Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.
Costa TJ, Potje SR, Fraga-Silva TFC, da Silva-Neto JA, Barros PR, Rodrigues D, Machado MR, Martins RB, Santos-Eichler RA, Benatti MN, de Sá KSG, Almado CEL, Castro ÍA, Pontelli MC, Serra L, Carneiro FS, Becari C, Louzada-Junior P, Oliveira RDR, Zamboni DS, Arruda E, Auxiliadora-Martins M, Giachini FRC, Bonato VLD, Zachara NE, Bomfim GF, Tostes RC. Costa TJ, et al. Among authors: santos eichler ra. Vascul Pharmacol. 2022 Feb;142:106946. doi: 10.1016/j.vph.2021.106946. Epub 2021 Nov 25. Vascul Pharmacol. 2022. PMID: 34838735 Free PMC article.
Mitochondrial DNA: A new driver for sex differences in spontaneous hypertension.
Echem C, Costa TJD, Oliveira V, Giglio Colli L, Landgraf MA, Rodrigues SF, Franco MDCP, Landgraf RG, Santos-Eichler RA, Bomfim GF, Akamine EH, de Carvalho MHC. Echem C, et al. Among authors: santos eichler ra. Pharmacol Res. 2019 Jun;144:142-150. doi: 10.1016/j.phrs.2019.04.008. Epub 2019 Apr 6. Pharmacol Res. 2019. PMID: 30965087
Anti-toll like receptor 4 (TLR4) therapy diminishes cardiac remodeling regardless of changes in blood pressure in spontaneously hypertensive rats (SHR).
Echem C, Bomfim GF, Ceravolo GS, Oliveira MA, Santos-Eichler RA, Bechara LR, Veras MM, Saldiva PH, Ferreira JC, Akamine EH, Fortes ZB, Dantas AP, de Carvalho MH. Echem C, et al. Among authors: santos eichler ra. Int J Cardiol. 2015;187:243-5. doi: 10.1016/j.ijcard.2015.03.190. Epub 2015 Mar 18. Int J Cardiol. 2015. PMID: 25838224 No abstract available.
Treatment with Standard and Low Dose of Conjugated Equine Estrogen Differentially Modulates Estrogen Receptor Expression and Response to Angiotensin II in Mesenteric Venular Bed of Surgically Postmenopausal Hypertensive Rats.
Araujo PX, Costa TJ, Echem C, Aparecida de Oliveira M, Santos-Eichler RA, Colli LG, Jiménez-Altayó F, Vila E, Akamine EH, Dantas AP, Ceravolo GS, de Carvalho MHC. Araujo PX, et al. Among authors: santos eichler ra. J Pharmacol Exp Ther. 2017 Jul;362(1):98-107. doi: 10.1124/jpet.117.240465. Epub 2017 May 22. J Pharmacol Exp Ther. 2017. PMID: 28533289
Detrimental Effects of Testosterone Addition to Estrogen Therapy Involve Cytochrome P-450-Induced 20-HETE Synthesis in Aorta of Ovariectomized Spontaneously Hypertensive Rat (SHR), a Model of Postmenopausal Hypertension.
Costa TJ, Ceravolo GS, Echem C, Hashimoto CM, Costa BP, Santos-Eichler RA, Oliveira MA, Jiménez-Altayó F, Akamine EH, Dantas AP, Carvalho MHC. Costa TJ, et al. Among authors: santos eichler ra. Front Physiol. 2018 May 8;9:490. doi: 10.3389/fphys.2018.00490. eCollection 2018. Front Physiol. 2018. PMID: 29867542 Free PMC article.
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