Santos JC - Search Results

1

Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.

Santos JC, Boucher D, Schneider LK, Demarco B, Dilucca M, Shkarina K, Heilig R, Chen KW, Lim RYH, Broz P. Santos JC, et al. Nat Commun. 2020 Jun 24;11(1):3276. doi: 10.1038/s41467-020-16889-z. Nat Commun. 2020. PMID: 32581219 Free PMC article.

2

Detecting Release of Bacterial dsDNA into the Host Cytosol Using Fluorescence Microscopy.

Dreier RF, Santos JC, Broz P. Dreier RF, et al. Among authors: santos jc. Methods Mol Biol. 2018;1714:199-213. doi: 10.1007/978-1-4939-7519-8_13. Methods Mol Biol. 2018. PMID: 29177864

3

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

Santos JC, Dick MS, Lagrange B, Degrandi D, Pfeffer K, Yamamoto M, Meunier E, Pelczar P, Henry T, Broz P. Santos JC, et al. EMBO J. 2018 Mar 15;37(6):e98089. doi: 10.15252/embj.201798089. Epub 2018 Feb 19. EMBO J. 2018. PMID: 29459437 Free PMC article.

4

Sensing of invading pathogens by GBPs: At the crossroads between cell-autonomous and innate immunity.

Santos JC, Broz P. Santos JC, et al. J Leukoc Biol. 2018 Oct;104(4):729-735. doi: 10.1002/JLB.4MR0118-038R. Epub 2018 Jul 18. J Leukoc Biol. 2018. PMID: 30020539 Review.

5

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.

Rühl S, Shkarina K, Demarco B, Heilig R, Santos JC, Broz P. Rühl S, et al. Among authors: santos jc. Science. 2018 Nov 23;362(6417):956-960. doi: 10.1126/science.aar7607. Science. 2018. PMID: 30467171

6

Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation.

Dilucca M, Ramos S, Shkarina K, Santos JC, Broz P. Dilucca M, et al. Among authors: santos jc. mBio. 2021 Aug 31;12(4):e0205421. doi: 10.1128/mBio.02054-21. Epub 2021 Aug 17. mBio. 2021. PMID: 34399626 Free PMC article.

7

Optogenetic activators of apoptosis, necroptosis, and pyroptosis.

Shkarina K, Hasel de Carvalho E, Santos JC, Ramos S, Leptin M, Broz P. Shkarina K, et al. Among authors: santos jc. J Cell Biol. 2022 Jun 6;221(6):e202109038. doi: 10.1083/jcb.202109038. Epub 2022 Apr 14. J Cell Biol. 2022. PMID: 35420640 Free PMC article.

8

Erratum for Dilucca et al., "Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation".

Dilucca M, Ramos S, Shkarina K, Santos JC, Broz P. Dilucca M, et al. Among authors: santos jc. mBio. 2023 Jun 27;14(3):e0069423. doi: 10.1128/mbio.00694-23. Epub 2023 Apr 11. mBio. 2023. PMID: 37039652 Free PMC article. No abstract available.

9

Structural basis of NINJ1-mediated plasma membrane rupture in cell death.

Degen M, Santos JC, Pluhackova K, Cebrero G, Ramos S, Jankevicius G, Hartenian E, Guillerm U, Mari SA, Kohl B, Müller DJ, Schanda P, Maier T, Perez C, Sieben C, Broz P, Hiller S. Degen M, et al. Among authors: santos jc. Nature. 2023 Jun;618(7967):1065-1071. doi: 10.1038/s41586-023-05991-z. Epub 2023 May 17. Nature. 2023. PMID: 37198476 Free PMC article.

10

NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis.

Ramos S, Hartenian E, Santos JC, Walch P, Broz P. Ramos S, et al. Among authors: santos jc. EMBO J. 2024 Apr;43(7):1164-1186. doi: 10.1038/s44318-024-00055-y. Epub 2024 Feb 23. EMBO J. 2024. PMID: 38396301 Free PMC article.

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