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A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Lyon M, Li P, Ferreira JJ, Lazarenko RM, Kharade SV, Kramer M, McClenahan SJ, Days E, Bauer JA, Spitznagel BD, Weaver CD, Borrego Alvarez A, Puga Molina LC, Lybaert P, Khambekar S, Liu A, Lindsley CW, Denton J, Santi CM. Lyon M, et al. Among authors: santi cm. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212338120. doi: 10.1073/pnas.2212338120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649421 Free PMC article.
K+ and Cl- channels and transporters in sperm function.
Santi CM, Orta G, Salkoff L, Visconti PE, Darszon A, Treviño CL. Santi CM, et al. Curr Top Dev Biol. 2013;102:385-421. doi: 10.1016/B978-0-12-416024-8.00014-3. Curr Top Dev Biol. 2013. PMID: 23287041 Free PMC article. Review.
SLO3 K+ channels control calcium entry through CATSPER channels in sperm.
Chávez JC, Ferreira JJ, Butler A, De La Vega Beltrán JL, Treviño CL, Darszon A, Salkoff L, Santi CM. Chávez JC, et al. Among authors: santi cm. J Biol Chem. 2014 Nov 14;289(46):32266-32275. doi: 10.1074/jbc.M114.607556. Epub 2014 Sep 30. J Biol Chem. 2014. PMID: 25271166 Free PMC article.
Src Kinase Is the Connecting Player between Protein Kinase A (PKA) Activation and Hyperpolarization through SLO3 Potassium Channel Regulation in Mouse Sperm.
Stival C, La Spina FA, Baró Graf C, Arcelay E, Arranz SE, Ferreira JJ, Le Grand S, Dzikunu VA, Santi CM, Visconti PE, Buffone MG, Krapf D. Stival C, et al. Among authors: santi cm. J Biol Chem. 2015 Jul 24;290(30):18855-64. doi: 10.1074/jbc.M115.640326. Epub 2015 Jun 9. J Biol Chem. 2015. PMID: 26060254 Free PMC article.
CFTR/ENaC-dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC.
Puga Molina LC, Pinto NA, Torres NI, González-Cota AL, Luque GM, Balestrini PA, Romarowski A, Krapf D, Santi CM, Treviño CL, Darszon A, Buffone MG. Puga Molina LC, et al. Among authors: santi cm. J Biol Chem. 2018 Jun 22;293(25):9924-9936. doi: 10.1074/jbc.RA118.003166. Epub 2018 May 9. J Biol Chem. 2018. PMID: 29743243 Free PMC article.
48 results