Santaguida S - Search Results

1

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.

Cohen-Sharir Y, McFarland JM, Abdusamad M, Marquis C, Bernhard SV, Kazachkova M, Tang H, Ippolito MR, Laue K, Zerbib J, Malaby HLH, Jones A, Stautmeister LM, Bockaj I, Wardenaar R, Lyons N, Nagaraja A, Bass AJ, Spierings DCJ, Foijer F, Beroukhim R, Santaguida S, Golub TR, Stumpff J, Storchová Z, Ben-David U. Cohen-Sharir Y, et al. Among authors: santaguida s. Nature. 2021 Feb;590(7846):486-491. doi: 10.1038/s41586-020-03114-6. Epub 2021 Jan 27. Nature. 2021. PMID: 33505028 Free PMC article.

2

Short- and long-term effects of chromosome mis-segregation and aneuploidy.

Santaguida S, Amon A. Santaguida S, et al. Nat Rev Mol Cell Biol. 2015 Aug;16(8):473-85. doi: 10.1038/nrm4025. Nat Rev Mol Cell Biol. 2015. PMID: 26204159 Free article. Review.

3

Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells.

Brennan CM, Vaites LP, Wells JN, Santaguida S, Paulo JA, Storchova Z, Harper JW, Marsh JA, Amon A. Brennan CM, et al. Among authors: santaguida s. Genes Dev. 2019 Aug 1;33(15-16):1031-1047. doi: 10.1101/gad.327494.119. Epub 2019 Jun 13. Genes Dev. 2019. PMID: 31196865 Free PMC article.

4

Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells.

Wang RW, Viganò S, Ben-David U, Amon A, Santaguida S. Wang RW, et al. Among authors: santaguida s. EMBO Rep. 2021 Aug 4;22(8):e52032. doi: 10.15252/embr.202052032. Epub 2021 Jun 8. EMBO Rep. 2021. PMID: 34105235 Free PMC article.

5

Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy.

Ippolito MR, Martis V, Martin S, Tijhuis AE, Hong C, Wardenaar R, Dumont M, Zerbib J, Spierings DCJ, Fachinetti D, Ben-David U, Foijer F, Santaguida S. Ippolito MR, et al. Among authors: santaguida s. Dev Cell. 2021 Sep 13;56(17):2440-2454.e6. doi: 10.1016/j.devcel.2021.07.006. Epub 2021 Aug 4. Dev Cell. 2021. PMID: 34352223 Free article.

6

Short-term molecular consequences of chromosome mis-segregation for genome stability.

Garribba L, De Feudis G, Martis V, Galli M, Dumont M, Eliezer Y, Wardenaar R, Ippolito MR, Iyer DR, Tijhuis AE, Spierings DCJ, Schubert M, Taglietti S, Soriani C, Gemble S, Basto R, Rhind N, Foijer F, Ben-David U, Fachinetti D, Doksani Y, Santaguida S. Garribba L, et al. Among authors: santaguida s. Nat Commun. 2023 Mar 11;14(1):1353. doi: 10.1038/s41467-023-37095-7. Nat Commun. 2023. PMID: 36906648 Free PMC article.

7

Generation of aneuploid cells and assessment of their ability to survive in presence of chemotherapeutic agents.

Ippolito MR, Santaguida S. Ippolito MR, et al. Among authors: santaguida s. Methods Cell Biol. 2024;182:21-33. doi: 10.1016/bs.mcb.2022.10.012. Epub 2022 Nov 24. Methods Cell Biol. 2024. PMID: 38359978

8

The life and miracles of kinetochores.

Santaguida S, Musacchio A. Santaguida S, et al. EMBO J. 2009 Sep 2;28(17):2511-31. doi: 10.1038/emboj.2009.173. Epub 2009 Jul 23. EMBO J. 2009. PMID: 19629042 Free PMC article. Review.

9

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine.

Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musacchio A. Santaguida S, et al. J Cell Biol. 2010 Jul 12;190(1):73-87. doi: 10.1083/jcb.201001036. J Cell Biol. 2010. PMID: 20624901 Free PMC article.

10

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.

Santaguida S, Vernieri C, Villa F, Ciliberto A, Musacchio A. Santaguida S, et al. EMBO J. 2011 Apr 20;30(8):1508-19. doi: 10.1038/emboj.2011.70. Epub 2011 Mar 15. EMBO J. 2011. PMID: 21407176 Free PMC article.

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