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Page 1
Showing results for snare tm
Search for Sanre TM instead (1 results)
Membrane fusion: grappling with SNARE and SM proteins.
Südhof TC, Rothman JE. Südhof TC, et al. Science. 2009 Jan 23;323(5913):474-7. doi: 10.1126/science.1161748. Science. 2009. PMID: 19164740 Free PMC article. Review.
Vesicular and target membrane-localized SNARE proteins zipper up into an alpha-helical bundle that pulls the two membranes tightly together to exert the force required for fusion. SM proteins, shaped like clasps, bind to trans-SNARE complexes to direct …
Vesicular and target membrane-localized SNARE proteins zipper up into an alpha-helical bundle that pulls the two membranes tig …
Molecular Mechanisms Underlying Neurotransmitter Release.
Rizo J. Rizo J. Annu Rev Biophys. 2022 May 9;51:377-408. doi: 10.1146/annurev-biophys-111821-104732. Epub 2022 Feb 15. Annu Rev Biophys. 2022. PMID: 35167762 Free PMC article. Review.
Major recent advances and previous data have led to a plausible model of how key proteins mediate neurotransmitter release. In this model, the soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptor (SNARE) proteins syntaxin-1, SNAP …
Major recent advances and previous data have led to a plausible model of how key proteins mediate neurotransmitter release. In this m …
SNARE Complex-Associated Proteins and Alcohol.
Das J. Das J. Alcohol Clin Exp Res. 2020 Jan;44(1):7-18. doi: 10.1111/acer.14238. Epub 2019 Dec 11. Alcohol Clin Exp Res. 2020. PMID: 31724225 Free PMC article. Review.
This article is an endeavor in this direction, focusing on the effect of EtOH on the presynaptic proteins associated with the neurotransmitter release machinery. Studies on the effects of EtOH at the levels of gene, protein, and behavior are highlighted in this article....
This article is an endeavor in this direction, focusing on the effect of EtOH on the presynaptic proteins associated with the neurotr …
v-SNARE function in chromaffin cells.
Dhara M, Mohrmann R, Bruns D. Dhara M, et al. Pflugers Arch. 2018 Jan;470(1):169-180. doi: 10.1007/s00424-017-2066-z. Epub 2017 Sep 8. Pflugers Arch. 2018. PMID: 28887593 Free PMC article. Review.
The machinery for vesicular release employs common molecular players in different model systems including neuronal and neuroendocrine cells, in particular members of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) protein family, Sec1/Mun …
The machinery for vesicular release employs common molecular players in different model systems including neuronal and neuroendocrine cells, …
SNARE Proteins in Synaptic Vesicle Fusion.
Palfreyman MT, West SE, Jorgensen EM. Palfreyman MT, et al. Adv Neurobiol. 2023;33:63-118. doi: 10.1007/978-3-031-34229-5_4. Adv Neurobiol. 2023. PMID: 37615864
Membrane fusion at synapses, as well as all trafficking steps of the secretory pathway, is mediated by SNARE proteins. The SNAREs are the minimal fusion machinery. They zipper from N-termini to membrane-anchored C-termini to form a 4-helix bundle that forces …
Membrane fusion at synapses, as well as all trafficking steps of the secretory pathway, is mediated by SNARE proteins. The …
Neuronal SNARE complex assembly guided by Munc18-1 and Munc13-1.
Wang S, Ma C. Wang S, et al. FEBS Open Bio. 2022 Nov;12(11):1939-1957. doi: 10.1002/2211-5463.13394. Epub 2022 Mar 22. FEBS Open Bio. 2022. PMID: 35278279 Free PMC article. Review.
Neurotransmitter release by Ca(2+) -triggered synaptic vesicle exocytosis is essential for information transmission in the nervous system. The soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs) syntaxin-1, SNAP-25, and synaptobrevin-2 fo …
Neurotransmitter release by Ca(2+) -triggered synaptic vesicle exocytosis is essential for information transmission in the nervous sy …
Gbetagamma SNARE Interactions and Their Behavioral Effects.
Alford S, Hamm H, Rodriguez S, Zurawski Z. Alford S, et al. Neurochem Res. 2019 Mar;44(3):636-649. doi: 10.1007/s11064-018-2531-x. Epub 2018 May 11. Neurochem Res. 2019. PMID: 29752624 Free PMC article. Review.
This directly or indirectly modifies action potential-evoked presynaptic Ca(2+) entry. In addition, Gbetagamma can interact directly with SNARE complexes responsible for synaptic vesicle fusion to reduce peak cleft neurotransmitter concentrations during evoked release. The …
This directly or indirectly modifies action potential-evoked presynaptic Ca(2+) entry. In addition, Gbetagamma can interact directly with …
Efficient fusion requires a membrane anchor on the vacuolar Qa-SNARE.
Wickner W, Lopes K, Song H, Rizo J, Orr A. Wickner W, et al. Mol Biol Cell. 2023 Aug 1;34(9):ar88. doi: 10.1091/mbc.E23-02-0052. Epub 2023 Jun 14. Mol Biol Cell. 2023. PMID: 37314849 Free PMC article.
Using the recombinant pure protein catalysts of yeast vacuole fusion, we now report that the specific distribution of transmembrane (TM) anchors on the Q-SNAREs is critical for efficient fusion. A TM anchor on the Qa-SNARE supports rapid fusion even wh …
Using the recombinant pure protein catalysts of yeast vacuole fusion, we now report that the specific distribution of transmembrane (TM …
Postsynaptic SNARE Proteins: Role in Synaptic Transmission and Plasticity.
Madrigal MP, Portalés A, SanJuan MP, Jurado S. Madrigal MP, et al. Neuroscience. 2019 Nov 10;420:12-21. doi: 10.1016/j.neuroscience.2018.11.012. Epub 2018 Nov 17. Neuroscience. 2019. PMID: 30458218 Free PMC article. Review.
Soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) proteins mediate membrane fusion events in eukaryotic cells. Traditionally recognized as major players in regulating presynaptic neurotransmitter release, accumulative evidence over recent …
Soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) proteins mediate membrane fusion events in eukar …
Down-regulation of OGT promotes cisplatin resistance by inducing autophagy in ovarian cancer.
Zhou F, Yang X, Zhao H, Liu Y, Feng Y, An R, Lv X, Li J, Chen B. Zhou F, et al. Theranostics. 2018 Oct 6;8(19):5200-5212. doi: 10.7150/thno.27806. eCollection 2018. Theranostics. 2018. PMID: 30555541 Free PMC article.
Functional analyses (in vitro and in vivo) were performed to confirm the role of OGT in cisplatin resistance. Autophagy-related proteins were tested by western blot. Transmission electron microscopy and mRFP-GFP-LC3 adenovirus reporter were used for autophagy flux a …
Functional analyses (in vitro and in vivo) were performed to confirm the role of OGT in cisplatin resistance. Autophagy-related proteins …
1,160 results