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Page 1
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.
Musa J, Cidre-Aranaz F, Aynaud MM, Orth MF, Knott MML, Mirabeau O, Mazor G, Varon M, Hölting TLB, Grossetête S, Gartlgruber M, Surdez D, Gerke JS, Ohmura S, Marchetto A, Dallmayer M, Baldauf MC, Stein S, Sannino G, Li J, Romero-Pérez L, Westermann F, Hartmann W, Dirksen U, Gymrek M, Anderson ND, Shlien A, Rotblat B, Kirchner T, Delattre O, Grünewald TGP. Musa J, et al. Among authors: sannino g. Nat Commun. 2019 Sep 11;10(1):4128. doi: 10.1038/s41467-019-12071-2. Nat Commun. 2019. PMID: 31511524 Free PMC article.
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.
Dallmayer M, Li J, Ohmura S, Alba Rubio R, Baldauf MC, Hölting TLB, Musa J, Knott MML, Stein S, Cidre-Aranaz F, Wehweck FS, Romero-Pérez L, Gerke JS, Orth MF, Marchetto A, Kirchner T, Bach H, Sannino G, Grünewald TGP. Dallmayer M, et al. Among authors: sannino g. Cell Death Dis. 2019 Feb 11;10(2):116. doi: 10.1038/s41419-019-1372-0. Cell Death Dis. 2019. PMID: 30741933 Free PMC article.
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, Romero-Pérez L, Hölting TLB, Amatruda JF, Cossarizza A, Henssen AG, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Grünewald TGP. Marchetto A, et al. Among authors: sannino g. Nat Commun. 2020 May 15;11(1):2423. doi: 10.1038/s41467-020-16244-2. Nat Commun. 2020. PMID: 32415069 Free PMC article.
Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, Romero-Pérez L, Hölting TLB, Amatruda JF, Cossarizza A, Henssen AG, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Grünewald TGP. Marchetto A, et al. Among authors: sannino g. Nat Commun. 2020 Nov 23;11(1):6068. doi: 10.1038/s41467-020-20017-2. Nat Commun. 2020. PMID: 33230121 Free PMC article.
Next steps in Ewing sarcoma (epi-)genomics.
Sannino G, Orth MF, Grünewald TG. Sannino G, et al. Future Oncol. 2017 Jun;13(14):1207-1211. doi: 10.2217/fon-2017-0159. Epub 2017 Jun 7. Future Oncol. 2017. PMID: 28589731 Free article. No abstract available.
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets.
Baldauf MC, Orth MF, Dallmayer M, Marchetto A, Gerke JS, Rubio RA, Kiran MM, Musa J, Knott MML, Ohmura S, Li J, Akpolat N, Akatli AN, Özen Ö, Dirksen U, Hartmann W, de Alava E, Baumhoer D, Sannino G, Kirchner T, Grünewald TGP. Baldauf MC, et al. Among authors: sannino g. Oncotarget. 2017 Aug 4;9(2):1587-1601. doi: 10.18632/oncotarget.20098. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416716 Free PMC article.
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.
Orth MF, Gerke JS, Knösel T, Altendorf-Hofmann A, Musa J, Alba-Rubio R, Stein S, Hölting TLB, Cidre-Aranaz F, Romero-Pérez L, Dallmayer M, Baldauf MC, Marchetto A, Sannino G, Knott MML, Wehweck F, Ohmura S, Li J, Hakozaki M, Kirchner T, Dandekar T, Butt E, Grünewald TGP. Orth MF, et al. Among authors: sannino g. Int J Cancer. 2019 Feb 15;144(4):859-867. doi: 10.1002/ijc.31903. Epub 2018 Dec 4. Int J Cancer. 2019. PMID: 30267407 Free article.
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
Sannino G, Marchetto A, Ranft A, Jabar S, Zacherl C, Alba-Rubio R, Stein S, Wehweck FS, Kiran MM, Hölting TLB, Musa J, Romero-Pérez L, Cidre-Aranaz F, Knott MML, Li J, Jürgens H, Sastre A, Alonso J, Da Silveira W, Hardiman G, Gerke JS, Orth MF, Hartmann W, Kirchner T, Ohmura S, Dirksen U, Grünewald TGP. Sannino G, et al. EBioMedicine. 2019 Sep;47:156-162. doi: 10.1016/j.ebiom.2019.08.002. Epub 2019 Aug 16. EBioMedicine. 2019. PMID: 31427232 Free PMC article.
Knott were supported by scholarships of the German National Academic Foundation. G. Sannino was supported by a scholarship from the Fritz-Thyssen Foundation (FTF-40.15.0.030MN). ...Dirksen is supported by grants from the German Cancer Aid (DKH-108128, DKH-70112018, …
Knott were supported by scholarships of the German National Academic Foundation. G. Sannino was supported by a scholarship fro …
Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma.
Gerke JS, Orth MF, Tolkach Y, Romero-Pérez L, Wehweck FS, Stein S, Musa J, Knott MML, Hölting TLB, Li J, Sannino G, Marchetto A, Ohmura S, Cidre-Aranaz F, Müller-Nurasyid M, Strauch K, Stief C, Kristiansen G, Kirchner T, Buchner A, Grünewald TGP. Gerke JS, et al. Among authors: sannino g. Int J Cancer. 2020 Apr 1;146(7):2036-2046. doi: 10.1002/ijc.32792. Epub 2019 Nov 29. Int J Cancer. 2020. PMID: 31732966 Free article.
Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
Steinestel K, Trautmann M, Jansen EP, Dirksen U, Rehkämper J, Mikesch JH, Gerke JS, Orth MF, Sannino G, Arteaga MF, Rossig C, Wardelmann E, Grünewald TGP, Hartmann W. Steinestel K, et al. Among authors: sannino g. Mol Oncol. 2020 Feb;14(2):248-260. doi: 10.1002/1878-0261.12610. Epub 2019 Dec 21. Mol Oncol. 2020. PMID: 31811703 Free PMC article.
85 results