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Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non-Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis.
Datar I, Sanmamed MF, Wang J, Henick BS, Choi J, Badri T, Dong W, Mani N, Toki M, Mejías LD, Lozano MD, Perez-Gracia JL, Velcheti V, Hellmann MD, Gainor JF, McEachern K, Jenkins D, Syrigos K, Politi K, Gettinger S, Rimm DL, Herbst RS, Melero I, Chen L, Schalper KA. Datar I, et al. Among authors: sanmamed mf. Clin Cancer Res. 2019 Aug 1;25(15):4663-4673. doi: 10.1158/1078-0432.CCR-18-4142. Epub 2019 May 3. Clin Cancer Res. 2019. PMID: 31053602 Free PMC article.
Direct effects of type I interferons on cells of the immune system.
Hervas-Stubbs S, Perez-Gracia JL, Rouzaut A, Sanmamed MF, Le Bon A, Melero I. Hervas-Stubbs S, et al. Among authors: sanmamed mf. Clin Cancer Res. 2011 May 1;17(9):2619-27. doi: 10.1158/1078-0432.CCR-10-1114. Epub 2011 Mar 3. Clin Cancer Res. 2011. PMID: 21372217 Free article. Review.
Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes.
Alfaro C, Suarez N, Oñate C, Perez-Gracia JL, Martinez-Forero I, Hervas-Stubbs S, Rodriguez I, Perez G, Bolaños E, Palazon A, Sanmamed MF, Morales-Kastresana A, Gonzalez A, Melero I. Alfaro C, et al. Among authors: sanmamed mf. PLoS One. 2011;6(12):e29300. doi: 10.1371/journal.pone.0029300. Epub 2011 Dec 20. PLoS One. 2011. PMID: 22206007 Free PMC article.
The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy.
Palazón A, Martínez-Forero I, Teijeira A, Morales-Kastresana A, Alfaro C, Sanmamed MF, Perez-Gracia JL, Peñuelas I, Hervás-Stubbs S, Rouzaut A, de Landázuri MO, Jure-Kunkel M, Aragonés J, Melero I. Palazón A, et al. Among authors: sanmamed mf. Cancer Discov. 2012 Jul;2(7):608-23. doi: 10.1158/2159-8290.CD-11-0314. Epub 2012 Jun 19. Cancer Discov. 2012. PMID: 22719018
Agonist antibodies to TNFR molecules that costimulate T and NK cells.
Melero I, Hirschhorn-Cymerman D, Morales-Kastresana A, Sanmamed MF, Wolchok JD. Melero I, et al. Among authors: sanmamed mf. Clin Cancer Res. 2013 Mar 1;19(5):1044-53. doi: 10.1158/1078-0432.CCR-12-2065. Clin Cancer Res. 2013. PMID: 23460535 Free PMC article.
Combined immunostimulatory monoclonal antibodies extend survival in an aggressive transgenic hepatocellular carcinoma mouse model.
Morales-Kastresana A, Sanmamed MF, Rodriguez I, Palazon A, Martinez-Forero I, Labiano S, Hervas-Stubbs S, Sangro B, Ochoa C, Rouzaut A, Azpilikueta A, Bolaños E, Jure-Kunkel M, Gütgemann I, Melero I. Morales-Kastresana A, et al. Among authors: sanmamed mf. Clin Cancer Res. 2013 Nov 15;19(22):6151-62. doi: 10.1158/1078-0432.CCR-13-1189. Epub 2013 Sep 12. Clin Cancer Res. 2013. PMID: 24030703
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