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Macrophage CD5L is a target for cancer immunotherapy.
Sanchez-Moral L, Paul T, Martori C, Font-Díaz J, Sanjurjo L, Aran G, Téllez É, Blanco J, Carrillo J, Ito M, Tuttolomondo M, Ditzel HJ, Fumagalli C, Tapia G, Sidorova J, Masnou H, Fernández-Sanmartín MA, Lozano JJ, Vilaplana C, Rodriguez-Cortés A, Armengol C, Valledor AF, Kremer L, Sarrias MR. Sanchez-Moral L, et al. Among authors: sanjurjo l. EBioMedicine. 2023 May;91:104555. doi: 10.1016/j.ebiom.2023.104555. Epub 2023 Apr 11. EBioMedicine. 2023. PMID: 37054630 Free PMC article.
Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake.
Amézaga N, Sanjurjo L, Julve J, Aran G, Pérez-Cabezas B, Bastos-Amador P, Armengol C, Vilella R, Escolà-Gil JC, Blanco-Vaca F, Borràs FE, Valledor AF, Sarrias MR. Amézaga N, et al. Among authors: sanjurjo l. J Leukoc Biol. 2014 Mar;95(3):509-20. doi: 10.1189/jlb.1212660. Epub 2013 Dec 2. J Leukoc Biol. 2014. PMID: 24295828
Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine.
Monguió-Tortajada M, Roura S, Gálvez-Montón C, Pujal JM, Aran G, Sanjurjo L, Franquesa M, Sarrias MR, Bayes-Genis A, Borràs FE. Monguió-Tortajada M, et al. Among authors: sanjurjo l. Theranostics. 2017 Jan 1;7(2):270-284. doi: 10.7150/thno.16154. eCollection 2017. Theranostics. 2017. PMID: 28042333 Free PMC article.
The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.
Matalonga J, Glaria E, Bresque M, Escande C, Carbó JM, Kiefer K, Vicente R, León TE, Beceiro S, Pascual-García M, Serret J, Sanjurjo L, Morón-Ros S, Riera A, Paytubi S, Juarez A, Sotillo F, Lindbom L, Caelles C, Sarrias MR, Sancho J, Castrillo A, Chini EN, Valledor AF. Matalonga J, et al. Among authors: sanjurjo l. Cell Rep. 2017 Jan 31;18(5):1241-1255. doi: 10.1016/j.celrep.2017.01.007. Cell Rep. 2017. PMID: 28147278 Free article.
Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury.
Perea L, Coll M, Sanjurjo L, Blaya D, Taghdouini AE, Rodrigo-Torres D, Altamirano J, Graupera I, Aguilar-Bravo B, Llopis M, Vallverdú J, Caballeria J, van Grunsven LA, Sarrias MR, Ginès P, Sancho-Bru P. Perea L, et al. Among authors: sanjurjo l. Hepatology. 2017 Sep;66(3):953-968. doi: 10.1002/hep.29215. Epub 2017 Jul 18. Hepatology. 2017. PMID: 28422322 Free PMC article.
CD5L is upregulated in hepatocellular carcinoma and promotes liver cancer cell proliferation and antiapoptotic responses by binding to HSPA5 (GRP78).
Aran G, Sanjurjo L, Bárcena C, Simon-Coma M, Téllez É, Vázquez-Vitali M, Garrido M, Guerra L, Díaz E, Ojanguren I, Elortza F, Planas R, Sala M, Armengol C, Sarrias MR. Aran G, et al. Among authors: sanjurjo l. FASEB J. 2018 Jul;32(7):3878-3891. doi: 10.1096/fj.201700941RR. Epub 2018 Feb 20. FASEB J. 2018. PMID: 29465313
Furthermore, functional experiments revealed that CD5L activates the UPR and autophagy mechanisms in Huh7 cells, thereby providing a novel molecular link between the UPR and autophagy in liver cancer.-Aran, G., Sanjurjo, L., Barcena, C., Simon-Coma, M., Tellez, E., …
Furthermore, functional experiments revealed that CD5L activates the UPR and autophagy mechanisms in Huh7 cells, thereby providing a novel m …
38 results